Department of Orthopaedic Surgery, University of California, San Diego, La Jolla, CA, USA.
Department of Neurosurgery, University of California, San Diego, La Jolla, CA, USA.
Neural Regen Res. 2014 Aug 15;9(16):1498-501. doi: 10.4103/1673-5374.139471.
Peripheral nerve injury impairs motor, sensory, and autonomic function, incurring substantial financial costs and diminished quality of life. For large nerve gaps, proximal lesions, or chronic nerve injury, the prognosis for recovery is particularly poor, even with autografts, the current gold standard for treating small to moderate nerve gaps. In vivo elongation of intact proximal stumps towards the injured distal stumps of severed peripheral nerves may offer a promising new strategy to treat nerve injury. This review describes several nerve lengthening strategies, including a novel internal fixator device that enables rapid and distal reconnection of proximal and distal nerve stumps.
周围神经损伤会损害运动、感觉和自主功能，造成巨大的经济成本和生活质量下降。对于大的神经间隙、近端损伤或慢性神经损伤，即使使用自体移植物（治疗小至中等神经间隙的金标准），其恢复的预后也特别差。将完整的近端残端向切断的周围神经的受损远端残端延长，可能为治疗神经损伤提供一种有前途的新策略。本文综述了几种神经延长策略，包括一种新的内置固定器装置，可实现近端和远端神经残端的快速和远端连接。
Zotero 插件