Li G, Wang H-T, Gao Y, Cui X-J, Zhang G-Z
Department of Urology, Second Hospital of Tianjin Medical University, Tianjin Institute of Urology, Tianjin, China.
Eur Rev Med Pharmacol Sci. 2014;18(18):2670-7.
To evaluate the CT characteristics of primary abdominopelvic desmoplastic small round cell tumor (DSCRT) and investigate the relation between radiologic features and corresponding clinicopathologic features.
A cohort study was performed on 12 abdominopelvic DSCRT patients, the preoperative computed tomography (CT) and contrast enhancement CT scan were performed in all cases. Tumor dimension, location, calcification, organs involvement, metastasis and enhancement characteristics were retrospectively evaluated and catalogued. Histopathology and serial immunological histological chemistry (IHC) studies were as diagnostic reference standard, all clinicopathological and radiological data were analyzed with emphasis on the corresponding imaging findings.
Abdominopelvic DSRCT mainly affects young males (male to female was 2:1), Predominantly, two individualized CT subtype patterns were noted according to its characteristic features and the most common imaging findings are extensively disseminated masses in the peritoneal cavity and/or mesentery with slight enhancement after administration of contrast (subtype 1, 9/12; 75%), the type was in correlated with the histopathologic findings of a large stromal component and scare of vessels or tumor cells. In subtype 2 (3/12; 25%), the tumor was solitary and bulky soft-tissue mass localized in retroperitoneum or retrovesical space, it manifested as heterogeneous enhancement which correlated well with the presence of abundance of microvessels and tumor cells.
Radiologically, abdomino-pelvic DSRCT is lack of pathognomonic CT character, the most common CT finding is multiple soft tissue masses or solitary bulky lesion inclined to extensively peritoneal and mesenteric spread with heterogeneous enhancement. These radiological findings are related to different histological compositions, awareness of these radiological features may facilitate the CT diagnosis.
评估原发性腹盆腔促结缔组织增生性小圆细胞肿瘤（DSCRT）的CT特征，并探讨影像学特征与相应临床病理特征之间的关系。
对12例腹盆腔DSCRT患者进行队列研究，所有病例均行术前计算机断层扫描（CT）及增强CT扫描。回顾性评估并记录肿瘤的大小、位置、钙化、器官受累情况、转移情况及增强特征。以组织病理学及系列免疫组织化学（IHC）研究作为诊断参考标准，重点分析所有临床病理和影像学数据及其相应的影像学表现。
腹盆腔DSRCT主要影响年轻男性（男女比例为2:1）。根据其特征，主要观察到两种个体化的CT亚型模式，最常见的影像学表现是腹腔和/或肠系膜内广泛分布的肿块，增强扫描后轻度强化（亚型1，9/12；75%），该型与大量间质成分及血管或肿瘤细胞稀少的组织病理学表现相关。在亚型2（3/12；25%）中，肿瘤为孤立的巨大软组织肿块，位于腹膜后或膀胱后间隙，表现为不均匀强化，这与丰富的微血管和肿瘤细胞的存在密切相关。
在影像学上，腹盆腔DSRCT缺乏特征性的CT表现，最常见的CT表现是多个软组织肿块或孤立的巨大病变，倾向于广泛的腹膜和肠系膜扩散且强化不均匀。这些影像学表现与不同的组织学组成有关，认识这些影像学特征可能有助于CT诊断。
