Wesley Keith, Wesley Karen
JEMS. 2014 Sep;39(9):27.
We collected EMS-reported "last known normal" (LKN) times for patients brought to the ED with suspected acute stroke and calculated the absolute difference between the neurologist-determined and EMS-reported LKN times (deltaLKN). We determined the rate of inappropriate IV tissue plasminogen activator (tPA) use if the EMS-reported times were used instead of the neurologist-determined times. Of 251 patients, mean and median deltaLKN were 28 and 0 minutes, respectively. deltaLKN was < 15 minutes in 91% of the entire group and < 15 minutes in 80% of patients with a diagnosis of stroke. Of patients who received IV tPA, none would've been incorrectly excluded from IV tPA if the EMS LKN time had been used. Conversely, of patients who didn't receive IV tPA, 6% would have been incorrectly included for IV tPA consideration had the EMS time been used. In patients with wake-up stroke symptoms, EMS underestimated LKN times by an average of 208 minutes. All of the potentially incorrectly included patients would've been wake-up strokes.
我们收集了因疑似急性卒中被送至急诊科的患者由紧急医疗服务(EMS)报告的“最后已知正常”(LKN)时间,并计算了神经科医生确定的LKN时间与EMS报告的LKN时间之间的绝对差值(deltaLKN)。如果使用EMS报告的时间而非神经科医生确定的时间,我们确定了不适当静脉注射组织型纤溶酶原激活剂(tPA)的使用率。在251例患者中,deltaLKN的平均值和中位数分别为28分钟和0分钟。在整个组中,91%的患者deltaLKN<15分钟,在诊断为卒中的患者中,80%的患者deltaLKN<15分钟。在接受静脉注射tPA的患者中,如果使用EMS的LKN时间,没有患者会被错误地排除在静脉注射tPA之外。相反,在未接受静脉注射tPA的患者中,如果使用EMS时间,6%的患者会被错误地纳入静脉注射tPA的考虑范围。在有醒后卒中症状的患者中,EMS对LKN时间的低估平均为208分钟。所有可能被错误纳入的患者均为醒后卒中。