Akaiwa Kei, Mitamura Yoshinori, Katome Takashi, Semba Kentaro, Egawa Mariko, Naito Takeshi
Department of Ophthalmology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto-cho, Tokushima 770-8503, Japan.
Case Rep Ophthalmol Med. 2014;2014:157242. doi: 10.1155/2014/157242. Epub 2014 Sep 23.
We present a case of prepapillary vascular loops complicated by a suspected macroaneurysm rupture which was treated with intravitreal bevacizumab (IVB). A 62-year-old woman presented with decreased vision and myodesopsia in her left eye. Her best-corrected visual acuity (BCVA) was 0.6 in the left eye. Fundus examination disclosed an elevated, round, and reddish lesion, retinal hemorrhage at the superior aspect of the optic disc, retinal opacification along the superior branch retinal artery, and a small vitreous hemorrhage. Optical coherence tomography showed a serous retinal detachment, and indocyanine green angiography demonstrated prepapillary vascular loops and a hypofluorescent area with hyperfluorescent margins. These findings suggested the presence of a macroaneurysm. No filling of the dye in the aneurysm-like dilatation suggested a blockage of the lumen with a thrombus which might be associated with a branch retinal artery occlusion (BRAO). A diagnosis of prepapillary vascular loops complicated by a suspected macroaneurysm rupture and BRAO was made. Because of a persistent serous retinal detachment, IVB was performed. One month later, the BCVA improved to 1.0. Fundus examination disclosed an organized yellowish-white macroaneurysm and resolution of the serous retinal detachment. We recommend careful monitoring of patients with prepapillary vascular loops because of complications such as macroaneurysm rupture and BRAO.
我们报告一例视乳头前血管襻合并疑似大动脉瘤破裂的病例,该病例采用玻璃体内注射贝伐单抗(IVB)进行治疗。一名62岁女性因左眼视力下降和飞蚊症就诊。她左眼的最佳矫正视力(BCVA)为0.6。眼底检查发现一个隆起、圆形、红色病变,视盘上方有视网膜出血,视网膜上支动脉沿线有视网膜混浊,以及少量玻璃体积血。光学相干断层扫描显示浆液性视网膜脱离,吲哚菁绿血管造影显示视乳头前血管襻和一个边缘高荧光的低荧光区。这些发现提示存在大动脉瘤。动脉瘤样扩张内无染料充盈提示管腔被血栓阻塞,这可能与视网膜分支动脉阻塞(BRAO)有关。诊断为视乳头前血管襻合并疑似大动脉瘤破裂及BRAO。由于浆液性视网膜脱离持续存在,遂行IVB治疗。1个月后,BCVA提高到1.0。眼底检查发现一个机化的黄白色大动脉瘤,浆液性视网膜脱离消退。由于存在大动脉瘤破裂和BRAO等并发症,我们建议对视乳头前血管襻患者进行密切监测。