Rashka P, Vykidal M
Acta Univ Palacki Olomuc Fac Med. 1989;123:271-8.
The present paper deals with the relation of rheumatoid arthritis to hepatic diseases. Rheumatoid arthritis is regarded as a general disease though the predominant articular symptoms are also accompanied by changes in other organs. Rheumatoid arthritis includes distinct dysproteinemia conditioning the positivity of the flocculation tests. This dysproteinemia is not identical with that found in hepatic diseases. The level of serum mucoproteids in case of liver damage is always lower and in rheumatoid arthritis higher. The elevated mucoprotein level makes the serum more resistant to flocculation, but his protective influence is only restricted and the flocculation cannot even be prevented by the considerably higher mucoproteid level of pronounced dysproteinemia. The specific nature of hepatic involvement could not be proved so far.
本文探讨类风湿性关节炎与肝脏疾病的关系。类风湿性关节炎虽以关节症状为主,但也伴有其他器官的病变,被视为一种全身性疾病。类风湿性关节炎存在导致絮状试验呈阳性的特殊蛋白血症。这种蛋白血症与肝脏疾病中的蛋白血症不同。肝损伤时血清粘蛋白水平总是较低,而类风湿性关节炎时则较高。粘蛋白水平升高使血清更不易发生絮状反应,但其保护作用有限,即使在明显蛋白血症时粘蛋白水平大幅升高也无法防止絮状反应。到目前为止,尚未证实肝脏受累的具体性质。