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额肌悬吊术治疗特发性眼睑痉挛和眼睑开合失用症患者——技术与结果

Frontalis suspension surgery to treat patients with essential blepharospasm and apraxia of eyelid opening-technique and results.

作者信息

Karapantzou Chrisanthi, Dressler Dirk, Rohrbach Saskia, Laskawi Rainer

机构信息

ENT-Department, University of Göttingen Medical Center, Göttingen, Germany.

出版信息

Head Face Med. 2014 Oct 22;10:44. doi: 10.1186/1746-160X-10-44.

Abstract

INTRODUCTION

We describe the results of 15 patients suffering from essential blepharospasm with apraxia of eyelid opening who underwent frontalis suspension surgery.

MATERIAL AND METHODS

Patients with apraxia of eyelid opening and unresponsive to botulinum toxin injections were studied. Bilateral frontalis suspension surgery was performed (sling operation) using polytetrafluoroethylene (Gore-Tex®) sutures. The patients reported the degree of improvement using a subjective rating scale to evaluate the benefit of the operation at two times after surgery (0-10 days and 180-360 days).

RESULTS

The patients reported a high degree of subjective improvement. In the early postoperative period (0-10 days) the mean degree of subjective improvement was 74.6% (standard deviation (SD) 26.4%). At 180-360 days after surgery the mean improvement was 70.0% (SD 26.7%). Small hematomas of the upper lid occurred postoperatively in all patients. Other complications were suture extrusions (9.1%), suture granulomas (6.1%), lacrimation (5.0%) and local infections (7.5%). Postoperatively, all patients needed additional botulinum toxin injections for optimal outcome.

CONCLUSION

Frontalis suspension surgery is a minimally invasive and effective treatment option for apraxia of eyelid opening in patients with essential blepharospasm unresponsive to botulinum toxin injections alone.

摘要

引言

我们描述了15例患有眼睑痉挛合并眼睑开合失用症的患者接受额肌悬吊手术的结果。

材料与方法

对眼睑开合失用且对肉毒杆菌毒素注射无反应的患者进行研究。使用聚四氟乙烯(戈尔特斯®)缝线进行双侧额肌悬吊手术(吊带手术)。患者使用主观评分量表报告改善程度,以评估术后两个时间点(术后0 - 10天和180 - 360天)手术的益处。

结果

患者报告主观改善程度较高。术后早期(0 - 10天)主观改善的平均程度为74.6%(标准差(SD)26.4%)。术后180 - 360天平均改善程度为70.0%(SD 26.7%)。所有患者术后上睑均出现小血肿。其他并发症包括缝线外露(9.1%)、缝线肉芽肿(6.1%)、流泪(5.0%)和局部感染(7.5%)。术后,所有患者都需要额外注射肉毒杆菌毒素以获得最佳效果。

结论

对于仅对肉毒杆菌毒素注射无反应的原发性眼睑痉挛患者的眼睑开合失用症,额肌悬吊手术是一种微创且有效的治疗选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/66bd/4213496/f06f689b6a0e/13005_2014_364_Fig1_HTML.jpg

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