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超声引导下双侧颈丛阻滞可减少甲状腺手术后的阿片类药物用量。

Ultrasound guided bilateral cervical plexus block reduces postoperative opioid consumption following thyroid surgery.

作者信息

Gürkan Yavuz, Taş Zafer, Toker Kamil, Solak Mine

机构信息

Kocaeli Üniversitesi Tıp Fakültesi Hastanesi, Umuttepe Kampüsü, 41380, Kocaeli, Turkey.

出版信息

J Clin Monit Comput. 2015 Oct;29(5):579-84. doi: 10.1007/s10877-014-9635-x. Epub 2014 Oct 26.

Abstract

Thyroid surgery may cause severe postoperative pain and discomfort for patients. Superficial cervical plexus block (SCPB) is one of the regional anesthesia techniques that can provide postoperative analgesia for thyroid surgery. The purpose of this study was to evaluate analgesic effect of ultrasound (US) guided SCPB in patients undergoing thyroid surgery. Fifty ASA I-II patients, aged 20-60, were included in this single blinded study. In a randomized and prospective manner patients were allocated to either SCPB or control group. Bilateral SCPB was performed preoperatively under US guidance using 10 ml 0.25 % bupivacaine for each side. Postoperative analgesia was provided with patient-controlled analgesia method with morphine intravenous. Primary outcome measure was postoperative opioid consumption and analyzed using Mann-Whitney U test. Secondary outcome measures were comparison of opioid side effects like nausea and vomiting and analyzed using Chi square test. VAS scores for pain at postoperative 1st, 6th, 12th, and 24th h were similar in SCPB and control groups (Median VAS values were 2.5, 3, 2, 0 and 3.5, 3, 2, 0 respectively). Postoperative morphine consumption was lower in SCPB group compared to control group at postoperative 6th, 12th, and 24th h (Median doses of morphine consumption were 4, 8, 9 and 5, 9, 11 mg respectively) (P < 0.05). Eight patients in the control group and six patients in the SCBP group had vomiting. Seven patients in the SCPB and none in the control group had hoarseness. Our study has shown that US guided SCPB has a significant analgesic effect in patients undergoing thyroid surgery. Further studies are required to search for the optimal LA dose during US guided SCPB.

摘要

甲状腺手术可能会给患者带来严重的术后疼痛和不适。颈浅丛阻滞(SCPB)是可为甲状腺手术提供术后镇痛的区域麻醉技术之一。本研究的目的是评估超声(US)引导下的SCPB对甲状腺手术患者的镇痛效果。本单盲研究纳入了50例年龄在20至60岁之间的美国麻醉医师协会(ASA)I-II级患者。患者以随机和前瞻性的方式被分配到SCPB组或对照组。术前在超声引导下双侧进行SCPB,每侧使用10 ml 0.25%布比卡因。术后采用吗啡静脉自控镇痛方法。主要观察指标是术后阿片类药物的消耗量,并使用曼-惠特尼U检验进行分析。次要观察指标是比较恶心和呕吐等阿片类药物副作用,并使用卡方检验进行分析。SCPB组和对照组术后第1、6、12和24小时的疼痛视觉模拟评分(VAS)相似(VAS中位数分别为2.5、3、2、0和3.5、3、2、0)。SCPB组术后第6、12和24小时的吗啡消耗量低于对照组(吗啡消耗量的中位数分别为4、8、9和5、9、11 mg)(P < 0.05)。对照组有8例患者、SCPB组有6例患者出现呕吐。SCPB组有7例患者出现声音嘶哑,对照组无患者出现声音嘶哑。我们的研究表明,超声引导下的SCPB对甲状腺手术患者有显著的镇痛效果。需要进一步研究以寻找超声引导下SCPB期间的最佳局麻药剂量。

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