13价肺炎球菌结合疫苗引入后儿童侵袭性肺炎球菌疾病的早期趋势：墨西哥一家医院八年主动监测结果
Early trends in invasive pneumococcal disease in children following the introduction of 13-valent pneumococcal conjugate vaccine: results from eight years of active surveillance in a Mexican hospital.
作者信息
Chacon-Cruz Enrigue, Rivas-Landeros R M, Volker-Soberanes M L
机构信息
Pediatric Infectious Diseases Service, Hospital General de Tijuana, Tijuana Baja-California, Paseo Centenario S/N, Zona Rio, Tijuana, Baja-California, ZC 22010, Mexico.
Microbiology Laboratory, Hospital General de Tijuana, Tijuana Baja-California, Mexico.
出版信息
Ther Adv Vaccines. 2014 Nov;2(6):155-8. doi: 10.1177/2051013614547199.
Abstract
BACKGROUND
In May 2012, universal vaccination with the 13-valent pneumococcal conjugate vaccine (PCV-13) was introduced for all children in the Tijuana region of Mexico, with a coverage of 80%.
METHOD
Between October 2005 and September 2013 active surveillance was undertaken for all invasive pneumococcal diseases (IPDs) in children admitted to the Tijuana General Hospital.
RESULTS
Following PCV-13 implementation, there was a 75% reduction in overall IPD, and no cases of serotype 19A, pneumococcal meningitis, and pneumococcal-associated deaths.
CONCLUSIONS
These results are the first to show the effectiveness of PCV-13 in Mexico.
摘要
背景
2012年5月，墨西哥蒂华纳地区所有儿童开始普遍接种13价肺炎球菌结合疫苗（PCV-13），接种率为80%。
方法
2005年10月至2013年9月，对蒂华纳总医院收治的儿童所有侵袭性肺炎球菌疾病（IPD）进行了主动监测。
结果
实施PCV-13疫苗接种后，总体IPD减少了75%，且未出现19A血清型、肺炎球菌脑膜炎及肺炎球菌相关死亡病例。
结论
这些结果首次表明PCV-13在墨西哥的有效性。
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