Zeidler S, Oudesluijs G G, Schoonderwaldt E M, Van Bever Y
Genet Couns. 2014;25(3):315-20.
Disruption in early pregnancy can cause severe and multiple congenital anomalies in a foetus. Three sequences, Limb-body wall complex (LBWC), amniotic band sequence (ABS) and body-stalk anomaly (BSA) are thought to be caused by disruption. This case report describes a foetus with severe multiple congenital anomalies, that fit the diagnoses of all three sequences, which might advocate these syndromes are a spectrum of one sequence.
孕早期的干扰可导致胎儿出现严重的多发性先天性异常。肢体-体壁复合体(LBWC)、羊膜带序列(ABS)和体蒂异常(BSA)这三种序列被认为是由干扰引起的。本病例报告描述了一名患有严重多发性先天性异常的胎儿,符合所有这三种序列的诊断,这可能表明这些综合征是一种序列的不同表现形式。