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后路内固定联合前路病灶清除融合术治疗多节段脊柱结核的疗效

The outcomes of combined posterior instrumentation and anterior radical debridement with fusion for multilevel spinal tuberculosis.

作者信息

Vamvanij Visit, Ruangchainikom Monchai, Thanapipatsiri Surin, Pichaisak Witchate

出版信息

J Med Assoc Thai. 2014 Sep;97 Suppl 9:S50-5.

Abstract

BACKGROUND

Aside from antituberculous drugs, anterior radical debridement with fusion has been recommended to eradicate the infectious foci and promote early bone healing in spinal tubercular patients. The addition of spinal instrumentation to stabilize the spine and restore physiologic alignment has also been proposed.

OBJECTIVE

This study was undertaken to evaluate the effectiveness of the combined posterior instrumentation and anterior spinal fusion procedure.

MATERIAL AND METHOD

Eleven consecutive patients who were diagnosed with tubercular spondylosis involving more than one vertebral level and who received combined posterior instrumentation and anterior spinal fusion were reviewed. The number of vertebrae involved was three levels in four patients and two levels in seven patients. There were 8 one-stage and 3 two-stage procedures. The mean follow-up time was 16 months (range 7-33). Patients were evaluated before and after surgery for kyphotic correction, fusion formation, and neurological status.

RESULTS

The average pre-operative, immediate postoperative, and last follow-up kyphotic angles were 40, 19, and 23 degrees, respectively. All patients obtained solid bony fusion, except for one who had partial graft dislodgment. There was no serious complication, such as neurological injury or deep wound infection.

CONCLUSION

Posterior instrumentation and anterior interbody fusion was effective in the management of multilevel spinal tuberculosis, as this procedure can effectively eradicate disease, provide bony fusion, correct deformity and prevent the progression of kyphosis.

摘要

背景

除抗结核药物外,对于脊柱结核患者,建议采用前路根治性清创融合术以根除感染灶并促进早期骨愈合。也有人提出增加脊柱内固定以稳定脊柱并恢复生理对线。

目的

本研究旨在评估后路内固定与前路脊柱融合联合手术的有效性。

材料与方法

回顾了11例连续诊断为累及一个以上椎体节段的结核性脊柱炎且接受后路内固定与前路脊柱融合联合手术的患者。受累椎体节段数为4例患者3个节段,7例患者2个节段。有8例一期手术和3例二期手术。平均随访时间为16个月(范围7 - 33个月)。对患者在手术前后进行后凸矫正、融合形成及神经功能状态评估。

结果

术前、术后即刻及末次随访时的平均后凸角分别为40度、19度和23度。除1例植骨部分移位外,所有患者均获得了牢固的骨融合。未发生严重并发症,如神经损伤或深部伤口感染。

结论

后路内固定与前路椎间融合术在多节段脊柱结核的治疗中是有效的,因为该手术能有效根除疾病、实现骨融合、矫正畸形并防止后凸进展。

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