Hamidi Sepehr, Stevens Ryan, DeClerck Brittney, Kim Gene H
Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
J Cutan Pathol. 2014 Dec;41(12):955-8. doi: 10.1111/cup.12420. Epub 2014 Dec 5.
Hydrophilic polymer coatings were designed to reduce friction between the catheter and vessel wall and facilitate intravascular manipulations during catheterization and placement of drug-eluting stents. One newly reported complication of such hydrophilic coatings is the fragmentation and embolization of the polymer, which can lead to ischemia and infarct by blocking the small vasculature. In this report, we present a patient with a non-healing ulcer on the leg. Biopsy from the ulcer revealed the presence of hydrophilic polymer emboli within the dermal vessels. This is one of the few reports of such a complication involving the skin. Our objective is to emphasize the histopathologic features of this uncommon iatrogenic phenomenon.
亲水性聚合物涂层旨在减少导管与血管壁之间的摩擦，并在导管插入和药物洗脱支架置入过程中便于血管内操作。这种亲水性涂层新报道的一种并发症是聚合物的破碎和栓塞，这可通过阻塞小血管导致局部缺血和梗死。在本报告中，我们介绍了一名腿部有不愈合溃疡的患者。溃疡活检显示真皮血管内存在亲水性聚合物栓子。这是涉及皮肤的此类并发症的少数报道之一。我们的目的是强调这种罕见的医源性现象的组织病理学特征。
