Li Li-Xia, Ai Kai Xin, Bai Yue Qin, Zhang Pin, Huang Xin-Yu, Li Yong-Yang
1 Department of Pharmacy, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine , Shanghai, China .
J Laparoendosc Adv Surg Tech A. 2014 Nov;24(11):770-6. doi: 10.1089/lap.2014.0225.
Laparoscopic cholecystectomy (LC) has been performed clinically for more than 20 years. However, the incidence of bile duct injury (BDI) remains high despite attempts to prevent and reduce it. The aim of this study was to use an intraoperative unfavorable factors ratings system to identify unfavorable intraoperative factors and evaluate the effectiveness of application of the system in reducing BDI during LC.
Between January 2009 and December 2010, 780 patients who underwent LC were reviewed retrospectively, including 384 LC patients without graded treatment of intraoperative unfavorable factors (GTIUF) during 2009 and 396 LC patients with routine GTIUF during 2010.
BDI was decreased significantly after routine GTIUF (5 cases without GTIUF versus 0 cases with routine GTIUF; P=.029). There was no significant difference in postoperative morbidity and mortality between the two groups. The mean operation duration of the routine GTIUF group was prolonged significantly (P<.0001). Laparoscopic cholecystitis grading, GTIUF, and doctor's experience were important factors affecting the duration of operation (P<.0001, P<.0001, and P<.0001, respectively).
GTIUF is an effective method that emphasizes identification of the course of the extrahepatic bile duct and reduces the occurrence of BDI, especially for inexperienced operators.
腹腔镜胆囊切除术(LC)已在临床上开展20多年。然而,尽管采取了预防和减少措施,胆管损伤(BDI)的发生率仍然很高。本研究的目的是使用一种术中不良因素评分系统来识别术中不良因素,并评估该系统在降低LC术中BDI发生率方面的应用效果。
回顾性分析2009年1月至2010年12月期间接受LC的780例患者,包括2009年未进行术中不良因素分级处理(GTIUF)的384例LC患者和2010年进行常规GTIUF的396例LC患者。
常规GTIUF后BDI显著降低(未进行GTIUF的有5例,进行常规GTIUF的为0例;P = 0.029)。两组术后发病率和死亡率无显著差异。常规GTIUF组的平均手术时间显著延长(P < 0.0001)。腹腔镜胆囊炎分级、GTIUF和医生经验是影响手术时间的重要因素(分别为P < 0.0001、P < 0.0001和P < 0.0001)。
GTIUF是一种有效的方法,强调识别肝外胆管走行,可减少BDI的发生,尤其对于经验不足的术者。