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[德国的中风发病率——保险数据与基于登记处数据的可比性]

[Stroke occurence in Germany - on the comparability of insurance data and registry-based data].

作者信息

Kohler M, Deutschbein J, Peschke D, Schenk L

机构信息

ZI-Praxispanel, Zentralinstitut für die Kassenärztliche Versorgung in Deutschland, Berlin.

Institut für Medizinische Soziologie und Rehabilitationswissenschaft, Charité - Universitätsmedizin Berlin.

出版信息

Fortschr Neurol Psychiatr. 2014 Nov;82(11):627-33. doi: 10.1055/s-0034-1385231. Epub 2014 Nov 10.

Abstract

PURPOSE

This article presents epidemiological data regarding stroke frequency in Germany based on nationwide statutory health insurance data (Deutsche BKK) and aims to analyse them in the context of current research. The comparability of the most important resources of stroke frequency data - stroke registers, DRG data and insurance data - is initially discussed in order to assess the presented data adequately.

METHODS

The study cohort comes from a population of about 1 000 000 people insured with BKK and consists of all persons who were treated for a stroke in an acute care hospital in 2007 (n = 4,843). Data were subjected to statistical secondary analysis including uni- and bivariate statistics and t tests. Reference studies for the observation period include data from GEK and AOK health insurances, from quality assurances Hessen and Bayern, from the ADSR, and hospital DRG data. The different study types are compared regarding their inclusion/exclusion criteria and the resulting effects on reported prevalences.

RESULTS

Different inclusion criteria and accordingly different operationalisations of "stroke" impede the comparability of existing German data resources regarding stroke. The inclusion of TIA, non-traumatic subdural haemorrhage (I62), and the frequency of unspecified strokes (I64) is especially inconsistent. In addition, recurrent strokes and the definition of first-ever strokes are treated differently. The study cohort reveals no major discrepancies regarding aetiological subgroups compared to previous results, only the percentage of women (60.3 %) seems exceptionally high.

CONCLUSIONS

The gender effect is attributed to the BKK member structure, and especially the high proportion of women in the older age groups. Discussion of stroke frequency in Germany needs to take structural differences between study types into account. There are two vulnerable groups that tend to be underrepresented: TIA patients with a high risk of recurrent strokes, and high-risk patients who have already had a stroke and are care-dependent, which are often unspecifically coded. In the future, study designs should include the whole range of stroke coding, thus enabling differentiated analyses.

摘要

目的

本文基于全国法定医疗保险数据(德国疾病保险协会数据)呈现德国中风发病率的流行病学数据,并旨在结合当前研究对其进行分析。为了充分评估所呈现的数据,首先讨论了中风发病率数据最重要的资源——中风登记册、疾病诊断相关分组(DRG)数据和保险数据——的可比性。

方法

研究队列来自约100万德国疾病保险协会参保人群,由2007年在急性护理医院接受中风治疗的所有患者组成(n = 4,843)。数据进行了统计二次分析,包括单变量和双变量统计以及t检验。观察期的参考研究包括来自GEK和AOK医疗保险、黑森州和巴伐利亚州质量保证、德国中风登记处(ADSR)的数据以及医院DRG数据。比较了不同研究类型的纳入/排除标准及其对报告患病率的影响。

结果

不同的纳入标准以及相应不同的“中风”操作定义妨碍了德国现有中风数据资源的可比性。短暂性脑缺血发作(TIA)、非创伤性硬膜下出血(I62)的纳入以及未明确类型中风(I64)的频率尤其不一致。此外,复发性中风和首次中风的定义处理方式也不同。与先前结果相比,研究队列在病因亚组方面没有重大差异,只是女性比例(60.3%)似乎异常高。

结论

性别效应归因于德国疾病保险协会的成员结构,尤其是老年组中女性比例较高。德国中风发病率的讨论需要考虑研究类型之间的结构差异。有两个易被忽视的群体:复发性中风风险高的TIA患者,以及已经中风且依赖护理的高危患者,这些患者的编码往往不具体。未来,研究设计应涵盖整个中风编码范围,从而能够进行差异化分析。

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