糖尿病性黄斑水肿治疗后曲安奈德的视网膜内沉积
Intraretinal deposition of triamcinolone acetonide after treatment of diabetic macular edema.
作者信息
Manjunath Varsha, Duker Jay S
机构信息
From the New England Eye Center, Tufts Medical Center, Boston, Massachusetts.
出版信息
Retin Cases Brief Rep. 2011 Summer;5(3):241-4. doi: 10.1097/ICB.0b013e3181e58624.
PURPOSE
To report a case of intraretinal triamcinolone acetonide crystal deposition visualized both clinically and on optical coherence tomography after intravitreal injection for diabetic macular edema refractory to focal/grid laser treatment.
METHODS
Observational case report. A 46-year-old man with severe bilateral diabetic macular edema underwent focal/grid laser therapy, Avastin (Genetech, Inc., South San Francisco, CA) injections, and multiple intravitreal triamcinolone acetonide treatments but remained refractory to treatment.
RESULTS
Visual acuity continued to worsen, and clinical and optical coherence tomography examination revealed scattered hyperreflective deposits throughout the retina.
CONCLUSION
Intravitreal triamcinolone acetonide can deposit within the retina after treatment of refractory diabetic macular edema.
目的
报告1例糖尿病性黄斑水肿患者，在接受局部/格栅激光治疗无效后行玻璃体腔注射曲安奈德，临床及光学相干断层扫描均发现视网膜内曲安奈德晶体沉积的病例。
方法
观察性病例报告。一名46岁患有严重双侧糖尿病性黄斑水肿的男性患者接受了局部/格栅激光治疗、阿瓦斯汀（基因泰克公司，加利福尼亚州南旧金山）注射以及多次玻璃体腔曲安奈德治疗，但治疗效果不佳。
结果
视力持续恶化，临床及光学相干断层扫描检查发现整个视网膜有散在的高反射沉积物。
结论
难治性糖尿病性黄斑水肿治疗后，玻璃体腔注射曲安奈德可在视网膜内沉积。
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