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[定量感觉测试]

[Quantitative sensory testing].

作者信息

Mücke M, Cuhls H, Radbruch L, Baron R, Maier C, Tölle T, Treede R-D, Rolke R

机构信息

Institut für Hausarztmedizin, Universitätsklinikum Bonn, Bonn, Deutschland,

出版信息

Schmerz. 2014 Dec;28(6):635-46; quiz 647-8. doi: 10.1007/s00482-014-1485-4.

Abstract

Quantitative sensory testing (QST) is a standardized and formalized set of clinical sensitivity tests based on subjective (psychophysical) methods, which depends on the cooperation of the subject being investigated. Calibrated stimuli are used to measure the perception and pain thresholds, which provide information on the presence of sensory plus or minus signs. The QST equipment presented mimics natural thermal or mechanical stimuli. The rationale is to test for patterns of functional sensory loss or gain by simultaneous assessment of both cutaneous and deep pain sensitivity. The majority of QST parameters are normally distributed only after logarithmic transformation (i.e. secondary normalization). With QST a complete somatosensory profile can be obtained within 1 h. The QST is a suitable method for characterizing the function of the somatosensory system in clinical trials and also in clinical practice as a diagnostic procedure.

摘要

定量感觉测试(QST)是一套基于主观(心理物理学)方法的标准化、规范化临床敏感性测试,它依赖于被调查对象的配合。使用经过校准的刺激来测量感知阈值和疼痛阈值,这些阈值可提供有关感觉阳性或阴性体征存在的信息。所展示的QST设备模拟自然热刺激或机械刺激。其基本原理是通过同时评估皮肤和深部疼痛敏感性来检测功能性感觉丧失或增强的模式。大多数QST参数仅在对数转换后(即二次标准化)呈正态分布。通过QST,可在1小时内获得完整的躯体感觉概况。QST是一种适用于在临床试验以及临床实践中作为诊断程序来表征躯体感觉系统功能的方法。

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