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华氏巨球蛋白血症:治疗还是不治疗?

Waldenstrom's macroglobulinaemia: to treat or not to treat?

作者信息

Sundriyal Deepak, Kumar Naveen, Kotwal Sumedha, Shirsi Nikhil

机构信息

Department of Medical Oncology, Dharamshila Hospital and Research Centre, New Delhi, India.

Department of Internal Medicine, PGIMER & Dr Ram Manohar Lohia Hospital, New Delhi, India.

出版信息

BMJ Case Rep. 2014 Nov 20;2014:bcr2014206875. doi: 10.1136/bcr-2014-206875.

Abstract

Waldenstrom's macroglobulinaemia (WM) is a rare lymphoproliferative disorder. It is mostly seen in the elderly population with a median age of 65 years at the time of diagnosis. The clinical presentation is variable and the patient may be entirely asymptomatic. The slow progressive nature of the disease allows many patients to survive for more than 5 years. At times it may be difficult for a clinician to determine the timing of therapy. We present an interesting case of WM that highlights the typical course of the disease and timing of its management.

摘要

华氏巨球蛋白血症(WM)是一种罕见的淋巴增殖性疾病。多见于老年人群,诊断时的中位年龄为65岁。临床表现多样,患者可能完全无症状。该疾病进展缓慢,许多患者可存活超过5年。有时临床医生很难确定治疗时机。我们报告一例有趣的WM病例,突出了该疾病的典型病程及其治疗时机。

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