Perl Jeffrey, Pierratos Andreas, Kandasamy Gokulan, McCormick Brendan B, Quinn Robert R, Jain Arsh K, Huang Anjie, Paterson J Michael, Oliver Matthew J
Division of Nephrology, St. Michael's Hospital, University of Toronto, Toronto, Ontario, Canada The Keenan Research Centre in the Li Ka Shing Knowledge Institute, St. Michael's Hospital, University of Toronto, Toronto, Ontario, Canada Division of Nephrology, University of Toronto, Toronto, Ontario, Canada Department of Medicine, Humber River Regional Hospital, University of Toronto, Toronto, Ontario, Canada.
Division of Nephrology, University of Toronto, Toronto, Ontario, Canada Department of Medicine, Humber River Regional Hospital, University of Toronto, Toronto, Ontario, Canada Ontario Renal Network, Toronto, Ontario, Canada.
Nephrol Dial Transplant. 2015 Feb;30(2):301-9. doi: 10.1093/ndt/gfu359. Epub 2014 Nov 20.
The likelihood of peritoneal dialysis (PD) utilization following a PD catheter insertion attempt is poorly described. We explored the risk factors for PD nonuse, focusing on the method of PD catheter implantation.
This population-based retrospective cohort study employed Ontario administrative health data to identify 3886 predialysis adults who had an incident PD catheter implantation between 2002 and 2010. The impact of the method of catheter implantation including open-surgical (open, n = 1884), surgical-laparoscopic (laparoscopic, n = 1154), nephrology-percutaneous (nephrology, n = 498) and radiology-percutaneous (radiology, n = 350) on rates of PD utilization (defined as four consecutive weeks of PD) was examined.
Eighty-three percent of study patients received PD. After adjustment, relative to patients with openly inserted catheters, PD utilization was greater for those with nephrology-inserted catheters [adjusted hazard ratio (aHR) 1.59, 95% confidence interval (CI) 1.29-1.95] and similar for radiology-inserted catheters [aHR 1.16, 95% CI 0.94-1.43] or laparoscopic-inserted catheters [aHR 0.97 (95% CI 0.86-1.09)]. Among PD nonusers, death occurred in 10% of the open group, 6% of the laparoscopic group, 27% of the radiology group and in fewer than 3% of the nephrology group. Sixty-nine percent received hemodialysis in the open group, 63% in the laparoscopic group, 61% in the radiology group and 88% in the nephrology group. Those remaining predialysis comprised 12% of the open group, 22% of the laparoscopic group, 11% of the radiology group and <3% of the nephrology group.
Nephrology insertion resulted in lower overall rates of PD nonuse, particularly due to death or remaining predialysis. Greater use may be related to insertion timing, technique or greater commitment on the part of nephrologists to the success of PD.
腹膜透析(PD)导管插入尝试后使用PD的可能性描述不足。我们探讨了不使用PD的危险因素,重点关注PD导管植入方法。
这项基于人群的回顾性队列研究利用安大略省行政卫生数据,确定了2002年至2010年间首次植入PD导管的3886名透析前成年人。研究了导管植入方法(包括开放手术(开放,n = 1884)、手术腹腔镜(腹腔镜,n = 1154)、肾内科经皮(肾内科,n = 498)和放射科经皮(放射科,n = 350))对PD使用率(定义为连续四周进行PD)的影响。
83%的研究患者接受了PD。调整后,与开放插入导管的患者相比,肾内科插入导管的患者PD使用率更高[调整后风险比(aHR)1.59,95%置信区间(CI)1.29 - 1.95],放射科插入导管的患者相似[aHR 1.16,95% CI 0.94 - 1.43],腹腔镜插入导管的患者也相似[aHR 0.97(95% CI 0.86 - 1.