von Alvensleben Johannes C, Dick Macdonald, Bradley David J, LaPage Martin J
University of Michigan, 1540 E. Hospital Dr, Ann Arbor, MI, 48109, USA,
J Interv Card Electrophysiol. 2014 Dec;41(3):273-7. doi: 10.1007/s10840-014-9946-3. Epub 2014 Nov 22.
Transseptal puncture (TSP) is commonly used to access the left heart for catheter ablation procedures. The specific complication risk of this procedure has not been determined. This study assesses the risk of TSP using a single standard technique during electrophysiology study (EPS) in pediatrics and congenital heart disease (CHD).
Retrospective cohort study of patients undergoing TSP during EPS at the University of Michigan Congenital Heart Center between 1999 and 2011.
There were 373 left heart ablation procedures during the study period. Excluded were six adults without CHD, five procedures using an alternative imaging modality, five procedures using retrograde aortic access, one transhepatic access, and one where TSP was performed during a prior procedure. Included were 321 pediatric (≤18 years old without CHD) TSP procedures (median age 13 years) and 34 TSP procedures in patients with CHD (median age 28 years). There was one complication directly attributable to TSP: needle perforation of the left atrium without development of effusion in the pediatric group. Post-procedure echocardiograms were performed in 351 (99 %) cases, showing only trivial effusions in seven (1.9 %).
This single center experience over 12 years shows the risk of TSP in pediatric and CHD patients to be low, with a 0.3 % (95 % confidence interval (CI) 0, 0.9 %) risk for complications directly related to TSP using only single plane fluoroscopy for visualization.
经房间隔穿刺术(TSP)常用于心脏导管消融手术中进入左心。该手术具体的并发症风险尚未确定。本研究评估了在儿科和先天性心脏病(CHD)患者的电生理研究(EPS)中使用单一标准技术进行经房间隔穿刺术的风险。
对1999年至2011年期间在密歇根大学先天性心脏病中心接受经房间隔穿刺术的患者进行回顾性队列研究。
研究期间共进行了373例左心消融手术。排除了6例无先天性心脏病的成人患者、5例使用替代成像方式的手术、5例使用逆行主动脉入路的手术、1例经肝入路手术以及1例在前次手术中进行经房间隔穿刺术的病例。纳入研究的有321例儿科(≤18岁无先天性心脏病)经房间隔穿刺术(中位年龄13岁)和34例先天性心脏病患者的经房间隔穿刺术(中位年龄28岁)。有1例并发症直接归因于经房间隔穿刺术:儿科组中左心房穿刺但未出现积液。351例(99%)患者术后进行了超声心动图检查,其中7例(1.9%)仅显示微量积液。
这项为期12年的单中心经验表明,儿科和先天性心脏病患者经房间隔穿刺术的风险较低,仅使用单平面荧光透视进行可视化时,与经房间隔穿刺术直接相关并发症的风险为0.3%(95%置信区间(CI)0,0.9%)。