Campese Vito M
Division of Nephrology, Keck School of Medicine, University of Southern California, Los Angeles, CA.
Semin Nephrol. 2014;34(5):571-6. doi: 10.1016/j.semnephrol.2014.08.011.
Hypertension associated with chronic kidney diseases often is resistant to drug treatment. This review deals with two main aspects of the management of CKD patients with hypertension: the role of sodium/volume and the need for dietary salt restriction, as well as appropriate use of diuretics and what currently is called sequential nephron blockade; the second aspect that is addressed extensively in this review is the role of the sympathetic nervous system and the possible clinical use of renal denervation.
与慢性肾脏病相关的高血压往往对药物治疗耐药。本综述探讨了慢性肾脏病合并高血压患者管理的两个主要方面：钠/容量的作用以及饮食限盐的必要性，以及利尿剂的合理使用和目前所谓的序贯肾单位阻断；本综述广泛探讨的第二个方面是交感神经系统的作用以及肾去神经支配可能的临床应用。
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