临床医生对使用药物洗脱隐形眼镜治疗青光眼的看法。
Clinicians' perspectives on the use of drug-eluting contact lenses for the treatment of glaucoma.
作者信息
Taniguchi Elise V, Kalout Patricia, Pasquale Louis R, Kohane Daniel S, Ciolino Joseph B
机构信息
Department of Ophthalmology, Massachusetts Eye & Ear Infirmary, Harvard Medical School, Boston, MA, USA.
出版信息
Ther Deliv. 2014 Oct;5(10):1077-83. doi: 10.4155/tde.14.76.
Glaucoma is the leading cause of irreversible blindness worldwide. The perspective of clinicians who treat the disease is important and may ultimately dictate the adoption of new treatment modalities, such as drug-eluting contact lenses. Recent advances have enabled contact lenses to serve as a sustained-release drug-delivery platform capable of treating glaucoma. This review covers the medical treatment of glaucoma, suboptimal adherence rates to treatment, and factors that may influence the clinical applicability of drug-eluting contact lenses. Ophthalmologists who treat glaucoma were surveyed to determine their perspective on treatment adherence, bandage contact lens use and the use of a drug-eluting contact lens to treat glaucoma. Given the challenge of treating glaucoma and the clinical need for improved drug delivery, drug-eluting contact lenses appear to be a promising treatment option.
青光眼是全球不可逆性失明的主要原因。治疗该疾病的临床医生的观点很重要，可能最终决定新治疗方式（如药物洗脱隐形眼镜）的采用。最近的进展使隐形眼镜能够作为一种能够治疗青光眼的缓释药物递送平台。本综述涵盖了青光眼的药物治疗、治疗依从率欠佳以及可能影响药物洗脱隐形眼镜临床适用性的因素。对治疗青光眼的眼科医生进行了调查，以确定他们对治疗依从性、绷带隐形眼镜的使用以及使用药物洗脱隐形眼镜治疗青光眼的看法。鉴于治疗青光眼的挑战以及改善药物递送的临床需求，药物洗脱隐形眼镜似乎是一种很有前景的治疗选择。
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