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胸主动脉瘤腔内修复术后的继发性主动脉食管瘘:文献综述及关于推测机制的新见解

Secondary aortoesophageal fistula after thoracic aortic aneurysm endovascular repair: literature review and new insights regarding the hypothesized mechanisms.

作者信息

Xi Er-Ping, Zhu Jian, Zhu Shui-Bo, Zhang Yu

机构信息

Department of Thoracic Cardiovascular Surgery, Wuhan General Hospital of Guangzhou Command Wuhan, 430070, Hubei Province, People's Republic of China.

出版信息

Int J Clin Exp Med. 2014 Oct 15;7(10):3244-52. eCollection 2014.

Abstract

BACKGROUND

Endovascular aortic repair was first performed nearly two decades ago and has become a well-established alternative therapy for many thoracoabdominal aortic diseases. Early survival results with the endovascular aortic repair were impressive, but it also brought many complications. Aortoesophageal fistula is little-known and may be underestimated because it is an unusual complication of thoracic endovascular aortic repair.

OBJECTIVE

To provide a review of the general features of aortoesophageal fistula as a little-known complication after thoracic endovascular aortic repair and to present a new insight regarding the hypothesized mechanisms of this complication based on clinical experience.

METHODS

The new insights regarding the hypothesized mechanisms built on the literature review and clinical experience. Literature Review from PubMed and Web of Knowledge for relevant studies with English paper. Searches were performed without year, and used the combinations of the following key words: "thoracic aortic aneurysm", "endovascular", "aortoesophageal fistula", "complication".

RESULTS

The authors' hypothesized mechanisms of aortoesophageal fistula after thoracic aortic aneurysm endovascular repair include the relatively thin vessel wall on thoracic aortic aneurysm hard to prevent the relatively rigid stent graft projecting the aortic and direct erosion into the esophagus.

CONCLUSION

Selecting flexibility and appropriate size stent graft, avoiding the thin aortic wall, and identifying the risk factors may reduce the morbidity of complications with aortoesophageal fistula after thoracic aortic aneurysm endovascular repair.

摘要

背景

血管腔内主动脉修复术首次实施于近二十年前,现已成为治疗多种胸腹主动脉疾病的成熟替代疗法。血管腔内主动脉修复术早期的生存结果令人印象深刻,但也带来了许多并发症。主动脉食管瘘鲜为人知,可能因其是胸段血管腔内主动脉修复术的一种罕见并发症而被低估。

目的

综述作为胸段血管腔内主动脉修复术后鲜为人知的并发症的主动脉食管瘘的一般特征,并基于临床经验对该并发症的推测机制提出新见解。

方法

基于文献综述和临床经验对推测机制提出新见解。从PubMed和Web of Knowledge检索相关英文研究文献。检索不限年份,使用以下关键词组合:“胸主动脉瘤”“血管腔内”“主动脉食管瘘”“并发症”。

结果

作者推测胸主动脉瘤血管腔内修复术后发生主动脉食管瘘的机制包括胸主动脉瘤血管壁相对较薄,难以防止相对坚硬的覆膜支架突出至主动脉并直接侵蚀食管。

结论

选择柔韧性好且尺寸合适的覆膜支架,避免主动脉壁过薄,并识别危险因素,可能会降低胸主动脉瘤血管腔内修复术后主动脉食管瘘并发症的发生率。

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