Interfaculty Initiative in Health Policy, Harvard University, Cambridge, Massachusetts.
Department of Health Care Policy, Harvard Medical School, Boston, Massachusetts3Massachusetts General Hospital, Boston4National Bureau of Economic Research, Cambridge, Massachusetts.
JAMA Intern Med. 2015 Feb;175(2):196-204. doi: 10.1001/jamainternmed.2014.5420.
Most out-of-hospital cardiac arrests receiving emergency medical services in the United States are treated by ambulance service providers trained in advanced life support (ALS), but supporting evidence for the use of ALS over basic life support (BLS) is limited.
To compare the effects of BLS and ALS on outcomes after out-of-hospital cardiac arrest.
DESIGN, SETTING, AND PARTICIPANTS: Observational cohort study of a nationally representative sample of traditional Medicare beneficiaries from nonrural counties who experienced out-of-hospital cardiac arrest between January 1, 2009, and October 2, 2011, and for whom ALS or BLS ambulance services were billed to Medicare (31,292 ALS cases and 1643 BLS cases). Propensity score methods were used to compare the effects of ALS and BLS on patient survival, neurological performance, and medical spending after cardiac arrest.
Survival to hospital discharge, to 30 days, and to 90 days; neurological performance; and incremental medical spending per additional survivor to 1 year.
Survival to hospital discharge was greater among patients receiving BLS (13.1% vs 9.2% for ALS; 4.0 [95% CI, 2.3-5.7] percentage point difference), as was survival to 90 days (8.0% vs 5.4% for ALS; 2.6 [95% CI, 1.2-4.0] percentage point difference). Basic life support was associated with better neurological functioning among hospitalized patients (21.8% vs 44.8% with poor neurological functioning for ALS; 23.0 [95% CI, 18.6-27.4] percentage point difference). Incremental medical spending per additional survivor to 1 year for BLS relative to ALS was $154,333.
Patients with out-of-hospital cardiac arrest who received BLS had higher survival at hospital discharge and at 90 days compared with those who received ALS and were less likely to experience poor neurological functioning.
在美国,大多数接受紧急医疗服务的院外心脏骤停患者由接受高级生命支持(ALS)培训的救护车服务提供商进行治疗,但 ALS 优于基本生命支持(BLS)的支持证据有限。
比较 BLS 和 ALS 对院外心脏骤停后结局的影响。
设计、地点和参与者:这是一项观察性队列研究,研究对象为来自非农村县的全国代表性样本中的传统 Medicare 受益人,他们在 2009 年 1 月 1 日至 2011 年 10 月 2 日期间经历了院外心脏骤停,并且 Medicare 为 ALS 或 BLS 救护车服务付费(31292 例 ALS 病例和 1643 例 BLS 病例)。采用倾向评分法比较 ALS 和 BLS 对心脏骤停后患者存活、神经功能和医疗支出的影响。
存活至出院、存活至 30 天和存活至 90 天;神经功能;以及每增加一名幸存者到 1 年的额外医疗支出。
接受 BLS 的患者存活至出院的比例更高(13.1%比 ALS 的 9.2%;4.0[95%CI,2.3-5.7]个百分点差异),存活至 90 天的比例也更高(8.0%比 ALS 的 5.4%;2.6[95%CI,1.2-4.0]个百分点差异)。接受 BLS 的住院患者神经功能更好(21.8%比 ALS 的 44.8%神经功能不良;23.0[95%CI,18.6-27.4]个百分点差异)。与 ALS 相比,BLS 每增加一名幸存者到 1 年的额外医疗支出为 154333.3 美元。
与接受 ALS 的患者相比,接受 BLS 的院外心脏骤停患者出院时和 90 天时的存活率更高,且神经功能不良的可能性更小。