烟雾病的头影测量特征：一项病例对照研究。

Cephalometric Features of Moyamoya Disease: A case control study.

作者信息

Qureshi Adnan I, Gilani Waqas I, Gilani Sarwat I, Adil Malik M

机构信息

Zeenat Qureshi Stroke Institute, St. Cloud MN.

出版信息

J Vasc Interv Neurol. 2014 Nov;7(4):13-8.

PMID:25422708

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4241409/

Abstract

CONTRIBUTION OF AUTHORS

Adnan I Qureshi, Waqas I Gilani MD, Sarwat I. Gilani MD, Malik M. Adil MD . Equally assisted in the synthesis and discussion of ideas, and share equal responsibility for the information written in the manuscript above.

CONFLICT OF INTEREST

No conflict of interests.

RUNNING TITLE

Cephalometric Features of Moyamoya Disease.

BACKGROUND

Moyamoya disease is highly prevalent among patients with syndromes that have unique cephalometric characteristics such as Down syndrome. We performed a case control study to investigate the relationship between cephalometric parameters and Moyamoya disease.

METHODS

Patients [aged 16-82 years] with angiographically confirmed Moyamoya disease who underwent cranial CT scan were analyzed. We identified three controls for each patient who were matched for age (±1 year), gender, and race (white or African American). The fronto-occipital diameter, bi-parietal diameter, and distance between bregma and occiput were measured from the head CT scans of cases and controls. The cephalic index was calculated by determining the ratio between bi-parietal diameter and fronto-occipital diameter and multiplying the value by 100.

RESULTS

A total of 13 cases of Moyamoya disease and 39 controls were analyzed. The stage of Moyamoya disease in cases was as follows: stage 1 (n=0), stage 2 (n=1), stage 3 (n=4), stage 4 (n=2), stage 5 (n=5) and stage 6 (n=1). There was a significantly greater bi-parietal diameter in Moyamoya disease patients compared with controls (141.5±3.7 mm versus 136.9±5.4 mm, p=0.007). There was a significantly greater fronto-occipital diameter in Moyamoya disease patients compared with controls (186.5±6.5 mm versus 180.2±8.7mm, p=0.02). The distance between bregma and occiput was shorter among cases compared with controls (81.1±6.2 versus 87.5±7.0, p=0.01).

CONCLUSIONS

We observed an association between cephalometric parameters and Moyamoya disease. Further study of the unique cephalometric characteristics among Moyamoya disease patients may provide additional insight into disease occurrence in white and African American populations.

摘要

作者贡献

阿德南·I·库雷希、瓦卡斯·I·吉拉尼医学博士、萨尔瓦特·I·吉拉尼医学博士、马利克·M·阿迪勒医学博士。同等协助观点的综合与讨论，并对上述稿件中所写信息承担同等责任。

利益冲突

无利益冲突。

标题

烟雾病的头影测量特征

背景

烟雾病在患有具有独特头影测量特征的综合征（如下文氏综合征）的患者中高度流行。我们进行了一项病例对照研究，以调查头影测量参数与烟雾病之间的关系。

方法

对经血管造影确诊为烟雾病且接受了头颅CT扫描的患者[年龄16 - 82岁]进行分析。我们为每位患者确定了三名年龄（±1岁）、性别和种族（白人或非裔美国人）匹配的对照。从病例和对照的头部CT扫描中测量额枕径、双顶径以及前囟与枕骨之间的距离。通过确定双顶径与额枕径的比值并将该值乘以100来计算头指数。

结果

共分析了13例烟雾病病例和39名对照。病例组烟雾病的分期如下：1期（n = 0）、2期（n = 1）、3期（n = 4）、4期（n = 2）、5期（n = 5）和6期（n = 1）。与对照组相比，烟雾病患者的双顶径显著更大（141.5±3.7毫米对136.9±5.4毫米，p = 0.007）。与对照组相比，烟雾病患者的额枕径显著更大（186.5±6.5毫米对180.2±8.7毫米，p = 0.02）。与对照组相比，病例组前囟与枕骨之间的距离更短（81.1±6.2对87.5±7.0，p = 0.01）。