三级医疗机构中就诊患者的玻璃体黄斑界面疾病发生率
Frequency of vitreomacular interface disease in patients presenting to a tertiary care institution.
作者信息
Xu Lucy T, Punjabi Omar S, Shao Jack, Ehlers Justis P, Srivastava Sunil K, Singh Rishi P, Kaiser Peter K
出版信息
Ophthalmic Surg Lasers Imaging Retina. 2014 Nov-Dec;45(6):517-20. doi: 10.3928/23258160-20141118-05.
BACKGROUND AND OBJECTIVE
To evaluate the frequency of vitreomacular interface disease using a recently published optical coherence tomography (OCT) classification and assess which of these patients would qualify for ocriplasmin.
PATIENTS AND METHODS
A retrospective, consecutive case series of patients with macular cyst, hole, or pseudohole (ICD-9 code 362.54) and concurrent OCT imaging was performed. Eyes were classified using OCT as pseudohole, lamellar hole, vitreomacular adhesion (VMA), vitreomacular traction (VMT), and full-thickness macular hole (FTMH). Minimum diameter (MD) of FTMH was measured.
RESULTS
The study included 399 eyes of 331 patients. Of these, 61 eyes (15.3%) had VMA or VMT, 120 (30.0%) had a lamellar hole or pseudohole, and 218 (54.6%) had FTMH. Of eyes with FTMH, 73 were small (< 250 µm MD), 48 were medium (250 to 400 µm MD), and 97 were large (> 400 µm MD). Overall, 68 eyes (17.0%) would be candidates for ocriplasmin therapy.
CONCLUSION
Most patients had FTMH, and 17% would qualify as candidates for ocriplasmin therapy.
背景与目的
使用最近发表的光学相干断层扫描（OCT）分类法评估玻璃体黄斑界面疾病的发生率，并评估这些患者中哪些符合使用奥克纤溶酶的条件。
患者与方法
对患有黄斑囊肿、裂孔或假性裂孔（国际疾病分类第九版代码362.54）并同时进行OCT成像的患者进行回顾性、连续病例系列研究。使用OCT将眼睛分类为假性裂孔、板层裂孔、玻璃体黄斑粘连（VMA）、玻璃体黄斑牵引（VMT）和全层黄斑裂孔（FTMH）。测量FTMH的最小直径（MD）。
结果
该研究纳入了331例患者的399只眼。其中，61只眼（15.3%）患有VMA或VMT，120只眼（30.0%）患有板层裂孔或假性裂孔，218只眼（54.6%）患有FTMH。在患有FTMH的眼中，73只为小裂孔（MD<250 µm），48只为中裂孔（MD为250至400 µm），97只为大裂孔（MD>400 µm）。总体而言，68只眼（17.0%）符合奥克纤溶酶治疗的条件。
结论
大多数患者患有FTMH，17%符合奥克纤溶酶治疗的条件。
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