6至22岁人群中巨细胞病毒抗体的患病率。

Prevalence of cytomegalovirus antibody in subjects between the ages of 6 and 22 years.

作者信息

White N H, Yow M D, Demmler G J, Norton H J, Hoyle J, Pinckard K, Mishaw C, Pokorny S

机构信息

Baylor College of Medicine, Department of Pediatrics, Houston, TX 77030.

出版信息

J Infect Dis. 1989 Jun;159(6):1013-7. doi: 10.1093/infdis/159.6.1013.

DOI:10.1093/infdis/159.6.1013

PMID:2542418

Abstract

We determined the prevalence of antibody to cytomegalovirus (CMV) in three groups between 1985 and 1987. Group I consisted of 511 subjects 6-22 y old, group II consisted of 920 subjects 18-21 y old, and group III of 113 subjects 18-22 y old. The overall prevalence of antibody in these three groups was 34%, 24%, and 28%, respectively. Prevalence of antibody in white subjects (24%, 21%, and 24%, respectively) was significantly lower than that in nonwhite subjects. In group I, there was no increase in prevalence with age in white subjects, but the percentage of individuals with antibody increased with age among nonwhite subjects. It is of obvious concern that a large proportion of white women entering childbearing years lack CMV antibody.

摘要

1985年至1987年间，我们测定了三组人群中巨细胞病毒（CMV）抗体的流行率。第一组由511名6至22岁的受试者组成，第二组由920名18至21岁的受试者组成，第三组由113名18至22岁的受试者组成。这三组人群中抗体的总体流行率分别为34%、24%和28%。白人受试者中抗体的流行率（分别为24%、21%和24%）显著低于非白人受试者。在第一组中，白人受试者的流行率没有随年龄增加，而非白人受试者中抗体阳性个体的百分比随年龄增加。大量进入生育年龄的白人女性缺乏CMV抗体，这显然令人担忧。