Litwic A, Cooper C, Dennison E
MRC Lifecourse Epidemiology Unit University of Southampton Southampton General Hospital, Southampton, UK -
Panminerva Med. 2014;56(4):273-83.
Osteoporosis is a systemic disorder characterized by low bone mass and microarchitectural deterioration of bone tissue with a consequent increase in bone fragility and susceptibility to fracture. It has a significant impact on public health through the increased morbidity, mortality, and economic costs associated with fractures. Despite the severe medical and socioeconomic consequences of fragility fractures, relatively few adults with fractures are evaluated and/or treated for osteoporosis. In this review, we summarize the existing treatment options and promising new therapies for the prevention and treatment of osteoporosis.
骨质疏松症是一种全身性疾病,其特征为骨量低和骨组织微结构破坏,进而导致骨脆性增加和骨折易感性增加。它通过与骨折相关的发病率、死亡率和经济成本增加,对公众健康产生重大影响。尽管脆性骨折会带来严重的医学和社会经济后果,但相对较少的骨折成年人会接受骨质疏松症的评估和/或治疗。在本综述中,我们总结了现有的治疗选择以及预防和治疗骨质疏松症的有前景的新疗法。