Chang Jung Hyun, Kim Jung Hyun, Kang Ju Wan, Kim Jeong Hong
Southeast Asian J Trop Med Public Health. 2014 Jul;45(4):869-73.
Tuberculosis is an important cause of morbidity and mortality world-wide. We report the case of a 52-year-old man who presented with a two month history of sore throat without other general or respiratory symptoms. Oral ex- amination revealed ulcerative and granulomatous lesions on the soft palate and tonsils. Histological examination of the lesions showed granulomatous tissue with caseaous necrosis consistent with tuberculosis. A chest x-ray and computed to- mography of the chest showed miliary tuberculosis of both lungs. The oral lesions improved with antituberculous medication by one month. Tuberculosis should be considered in the differential diagnosis of oral lesions which do not respond to appropriate antibiotic therapy. Pulmonary tuberculosis should also be considered in patients with oral tuberculosis even if they do not have respiratory symptoms.
结核病是全球发病和死亡的重要原因。我们报告一例52岁男性病例,该患者有两个月的咽痛病史,无其他全身或呼吸道症状。口腔检查发现软腭和扁桃体有溃疡性和肉芽肿性病变。病变的组织学检查显示肉芽肿组织伴有干酪样坏死,符合结核病表现。胸部X线和胸部计算机断层扫描显示双肺粟粒性结核。经抗结核药物治疗1个月后,口腔病变有所改善。对于对适当抗生素治疗无反应的口腔病变,鉴别诊断时应考虑结核病。即使患有口腔结核的患者没有呼吸道症状,也应考虑同时存在肺结核。