Degenhart Christoph, Strube Hanna, Betz Matthias J, Pallauf Anna, Bidlingmaier Martin, Fischer Evelyn, Reincke Martin, Reiser Maximilian F, Wirth Stefan
Institute for Clinical Radiology, Ludwig-Maximilians-University Hospital Munich, Munich, Germany.
Diagn Interv Radiol. 2015 Jan-Feb;21(1):60-6. doi: 10.5152/dir.2014.14026.
We aimed to evaluate the accuracy of multidetector computed tomography (MDCT) venous mapping for the localization of the right adrenal veins (RAV) in patients suffering from primary aldosteronism.
MDCT scans of 75 patients with primary aldosteronism between March 2008 and November 2011 were evaluated by two readers (a junior [R1] and a senior [R2] radiologist) according to the following criteria: quality of RAV depiction (scale, 1-5), localization of the RAV confluence with regard to the inferior vena cava, and depiction of anatomical variants. Results were compared with RAV venograms obtained during adrenal vein sampling and corroborated by laboratory testing of cortisol in selective RAV blood samples. Kappa statistics were calculated for interobserver agreement and for concordance of MDCT mapping with the gold standard.
Successful RAV sampling was achieved in 69 of 75 patients (92%). Using MDCT mapping, adrenal veins could be visualized in 78% (R1, 54/69) and 77% (R2, 53/69) of patients. MDCT mapping led to correct identification of RAV in 70% (R1, 48/69) and 88% (R2, 61/69) of patients. Venograms revealed five cases of anatomical variants, which were correctly identified in 60% (R1, R2). MDCT-based localizations were false or misleading in 16% (R1, 11/69) and 7% (R2, 5/69) of cases.
Preinterventional MDCT mapping may facilitate successful catheterization in adrenal vein sampling.
我们旨在评估多排螺旋计算机断层扫描(MDCT)静脉造影对原发性醛固酮增多症患者右肾上腺静脉(RAV)定位的准确性。
对2008年3月至2011年11月期间75例原发性醛固酮增多症患者的MDCT扫描结果,由两名阅片者(一名初级[R1]和一名高级[R2]放射科医生)按照以下标准进行评估:RAV显示质量(评分,1 - 5)、RAV汇合处相对于下腔静脉的定位以及解剖变异的显示。将结果与肾上腺静脉采血期间获得的RAV静脉造影结果进行比较,并通过选择性RAV血样中皮质醇的实验室检测进行证实。计算观察者间一致性以及MDCT造影与金标准一致性的Kappa统计量。
75例患者中有69例(92%)成功进行了RAV采血。使用MDCT造影,78%(R1,54/69)和77%(R2,53/69)的患者肾上腺静脉可被可视化。MDCT造影在70%(R1,48/69)和88%(R2,61/69)的患者中能够正确识别RAV。静脉造影显示5例解剖变异,其中60%(R1、R2)被正确识别。基于MDCT的定位在16%(R1,11/69)和7%(R2,5/69)的病例中出现错误或误导。
介入前MDCT造影可能有助于肾上腺静脉采血的成功插管。