Granieri Michael A, Webster George D, Peterson Andrew C
Division of Urology, Department of Surgery, Duke University Medical Center, Durham, NC.
Division of Urology, Department of Surgery, Duke University Medical Center, Durham, NC.
Urology. 2014 Dec;84(6):1511-5. doi: 10.1016/j.urology.2014.08.010.
To examine the timing, incidence, and resolution of scrotal and perineal sensory neuropathy after urethroplasty for bulbar urethral stricture disease.
We performed an institutional review board--approved retrospective review of our urethroplasty database with specific attention paid to patient demographics, stricture location, repair type, and postoperative sensory neuropathy defined as the complaint of hypesthesia, anesthesia, paresthesia, hyperesthesia, and pain in the scrotal and perineal region after surgery. Incidence and reported times to onset and resolution of sensory neuropathy were compared among our cohort.
A total of 155 men underwent urethroplasty for bulbar urethral stricture disease from January 2007 to December 2012. One hundred forty-three of 155 men (92%) had postoperative data available for analysis. The average age at surgery was 47 ± 15 years and average stricture length was 2.1 ± 1.4 cm. Repair types were excision and primary anastomosis (101 of 143; 71%), augmented anastomotic repair (31 of 143; 22%), onlay repair (4 of 143; 3%), and perineal urethrostomy (7/143, 5%). Twenty of 143 men (14%) experienced postoperative scrotal and perineal neuralgia at a median time of 108 days (range, 18-160 days) from surgery. Fourteen of 20 men (70%) had subsequent follow-up visits, and all of these men had resolution of the pain, without treatment, at a median reported time of 271 days from surgery. There were no significant differences in incidence, resolution, or timing of sensory neuropathy among repair types.
Our findings indicate that approximately 14% of men who undergo urethroplasty for bulbar urethral stricture disease experience postoperative scrotal and perineal sensory neuropathy. This appears to be transient with 100% resolution in our patients with available follow-up.
探讨球部尿道狭窄疾病行尿道成形术后阴囊及会阴感觉神经病变的发生时间、发生率及恢复情况。
我们对尿道成形术数据库进行了一项经机构审查委员会批准的回顾性研究,特别关注患者人口统计学资料、狭窄部位、修复类型以及术后感觉神经病变,术后感觉神经病变定义为术后阴囊及会阴区域出现感觉减退、感觉缺失、感觉异常、感觉过敏及疼痛的主诉。我们比较了队列中感觉神经病变的发生率以及报告的发病时间和恢复时间。
2007年1月至2012年12月,共有155例男性因球部尿道狭窄疾病接受尿道成形术。155例男性中有143例(92%)有术后数据可供分析。手术时的平均年龄为47±15岁,平均狭窄长度为2.1±1.4cm。修复类型包括切除并一期吻合(143例中的101例;71%)、增强吻合修复(143例中的31例;22%)、覆盖修复(143例中的4例;3%)以及会阴尿道造口术(143例中的7例,5%)。143例男性中有20例(14%)在术后出现阴囊及会阴神经痛,中位时间为术后108天(范围18 - 160天)。20例男性中有14例(70%)进行了后续随访,所有这些男性在未接受治疗的情况下,疼痛在术后中位时间271天得到缓解。不同修复类型之间在感觉神经病变的发生率、恢复情况或发生时间方面无显著差异。
我们的研究结果表明,约14%因球部尿道狭窄疾病接受尿道成形术的男性会出现术后阴囊及会阴感觉神经病变。在我们有随访资料的患者中,这种病变似乎是暂时的,100%可恢复。