印度人群中糖尿病与视网膜血管灰度分形维数的关系。
Relationship between diabetes and grayscale fractal dimensions of retinal vasculature in the Indian population.
作者信息
Aliahmad Behzad, Kumar Dinesh Kant, Sarossy Marc George, Jain Rajeev
机构信息
School of Electrical and Computer Engineering, RMIT University, Melbourne, Australia.
出版信息
BMC Ophthalmol. 2014 Dec 1;14:152. doi: 10.1186/1471-2415-14-152.
BACKGROUND
Diabetes mellitus is rapidly increasing in the Indian population. The purpose of this study was to identify changes in the retinal vasculature of diabetic people, ahead of visual impairments. Grayscale Fractal Dimension (FD) analysis of retinal images was performed on people with type 2 diabetes from an Indian population.
METHODS
A cross-sectional study comprising 189 Optic Disc (OD) centred retinal images of healthy and diabetic individuals aged 14 to 73 years was conducted. Grayscale Box Counting FD of these retinal photographs was measured without manual supervision. Statistical analysis was conducted to determine the difference in the FD between diabetic and healthy (non-diabetic) people.
RESULTS
The results show that grayscale FD values for diabetic cases are higher compared to controls, irrespective of the gender. It was also observed that FD was higher for male compared with females.
CONCLUSIONS
There is difference in the grayscale fractal dimension of retinal vasculature of diabetic patients and healthy subjects, even when there is no reported retinopathy.
背景
糖尿病在印度人群中的发病率正在迅速上升。本研究的目的是在视力受损之前，识别糖尿病患者视网膜血管的变化。对来自印度人群的2型糖尿病患者的视网膜图像进行了灰度分形维数（FD）分析。
方法
开展了一项横断面研究，纳入了189张以视盘（OD）为中心的、年龄在14至73岁的健康个体和糖尿病个体的视网膜图像。在无人工监督的情况下测量了这些视网膜照片的灰度盒计数分形维数。进行统计分析以确定糖尿病患者和健康（非糖尿病）人群之间分形维数的差异。
结果
结果表明，无论性别如何，糖尿病病例的灰度分形维数均高于对照组。还观察到男性的分形维数高于女性。
结论
即使没有报告视网膜病变，糖尿病患者和健康受试者视网膜血管的灰度分形维数也存在差异。
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