1 型神经纤维瘤病合并十二指肠乳头腺癌 1 例
A case of periampullary adenocarcinoma in neurofibromatosis type 1.
机构信息
1 Department of Medicine, 2 Department of Medical Oncology, 3 Department of Surgery, 4 Department of Pathology, 5 Department of Medicine, Division of Gastroenterology and Hepatology, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
出版信息
J Gastrointest Oncol. 2014 Dec;5(6):E96-9. doi: 10.3978/j.issn.2078-6891.2014.047.
Abstract
Neurofibromatosis type 1 (NF-1) is an autosomal dominant genetic disorder with a known predisposition to gastrointestinal neoplasms such as stromal tumors and carcinoids. Adenocarcinomas (ACs) of the gastrointestinal tract are relatively rare in patients with NF-1, especially those found in the periampullary region. We present a case report of periampullary adenocarcinoma in a 56-year-old woman with NF-1 who presented with abdominal pain and obstructive jaundice.
摘要
神经纤维瘤病 1 型（NF-1）是一种常染色体显性遗传疾病，已知易患胃肠道肿瘤，如基质肿瘤和类癌。胃肠道的腺癌（ACs）在 NF-1 患者中相对少见，特别是在壶腹周围区域发现的 ACs。我们报告了一例 NF-1 女性患者的壶腹周围腺癌病例，该患者出现腹痛和阻塞性黄疸。
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