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A 14-year old girl with reversible hypoglycemic episodes: the role of ASVS.

作者信息

Smith Alisha, Thornton Paul S, Galliani Carlos A, Miller James P, Dykes Jennifer, Leung-Pineda Van

机构信息

1 Department of Pathology and Laboratory, Cook Children's Medical Center, Fort Worth, Texas 76104, USA.

出版信息

Pediatr Dev Pathol. 2015 Jan-Feb;18(1):80-3. doi: 10.2350/14-08-1537-CR.1. Epub 2014 Dec 1.

Abstract

We present the case of a 14-year-old female who experienced several episodes of reversible altered mental status triggered by hypoglycemia. Following endocrine investigation, she was diagnosed with insulinoma. Insulinoma, a rare, differentiated, and functioning neuroendocrine tumor of the pancreas overproduces insulin, thus leading to hypoglycemic episodes. Conventional imaging failed to detect the lesion; therefore, arterial calcium stimulation with venous sampling (ASVS) was used for preoperative localization. The patient recovered without complications after surgical enucleation of the tumor. The ASVS is a useful method for localizing insulinomas when conventional imaging techniques fail, and can help reduce morbidities associated with surgical excision.

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