Koro'lkova E L, Lozovskaia L S, Tadtaeva L I, Khellenov E A
Kardiologiia. 1989 Jan;29(1):68-71.
Sixty-two children with congenital heart diseases and 100 normal children were examined, their age ranging from 5 days to 6 years. Indicators of intrauterine enterovirus infection risk were detected in 93.5% of children with congenital heart diseases and in just 21.9% of the controls. Coxsackie A and B viruses were detected by immunofluorescence in urinary sediment cells of 84.4% of children with congenital heart diseases vs. 7.7% of the controls. None of the 20 serotypes of Coxsackie A virus was detected at a predominant rate, as compared to others. Among the Coxsackie B serotypes, Coxsackie virus B3 was recovered particularly frequently. Etiologic relationship of congenital heart diseases to Coxsackie virus infection, and possible persistence of these viruses in children with congenital heart diseases are discussed.
对62名先天性心脏病患儿和100名正常儿童进行了检查，他们的年龄在5天至6岁之间。在93.5%的先天性心脏病患儿中检测到宫内肠道病毒感染风险指标，而在对照组中这一比例仅为21.9%。通过免疫荧光法在84.4%的先天性心脏病患儿尿沉渣细胞中检测到柯萨奇A组和B组病毒，而在对照组中这一比例为7.7%。与其他血清型相比，未检测到20种柯萨奇A组病毒血清型中的任何一种占主导比例。在柯萨奇B组血清型中，柯萨奇病毒B3的检出尤为频繁。讨论了先天性心脏病与柯萨奇病毒感染的病因关系，以及这些病毒在先天性心脏病患儿中可能的持续存在情况。
Zotero 插件