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[视觉雪现象。]

[The visual snow phenomenon.].

作者信息

Zambrowski O, Ingster-Moati I, Vignal-Clermont C, Robert M P

机构信息

Service d'ophtalmologie, hôpital universitaire Necker-Enfants malades, 149, rue de Sèvres, 75743 Paris cedex 15, France; Service d'ophtalmologie, centre hospitalier intercommunal, 40, avenue de Verdun, 94000 Créteil, France.

Service d'ophtalmologie, hôpital universitaire Necker-Enfants malades, 149, rue de Sèvres, 75743 Paris cedex 15, France; UFR de médecine université Paris 7 Diderot, 10, avenue de Verdun, 75010 Paris, France.

出版信息

J Fr Ophtalmol. 2014 Nov;37(9):722-727. doi: 10.1016/j.jfo.2014.08.001. Epub 2014 Oct 14.

Abstract

INTRODUCTION

Visual snow is a symptom described by some patients and poorly recognized by ophthalmologists. It consists in the permanent perception of a textured or a snowy vision, sometimes associated with palinopsia, exaggerated perception of the blue field entoptic phenomenon and photophobia. We report a group of patients suffering from visual snow in order to precise its characteristics and discuss its pathophysiology.

MATERIALS AND METHODS

Prospective study of patients diagnosed between September 2010 and December 2012 with a visual snow phenomenon. For each patient, a formal ophthalmologic examination, an Amsler grid test, an automated visual field (central 20°), a color vision test (15 Hue), a full field, a pattern and a multifocal electroretinogram as well as flash and pattern visual evoked potentials (Métrovision) were performed. A brain imaging was not systematically performed.

RESULTS

Twelve patients aged 9-48old were included (six men and six women, 85 % of students). Several signs were variably associated with the visual snow phenomenon: palinopsia (50 %), constant blue field entoptic phenomenon (40 %), photophobia (30 %), migraine (30 %); in 20 % of cases, an initial toxic intake was found (20 %).

DISCUSSION

This study highlights the reproducibility of typical symptoms described by patients reporting the visual snow phenomenon. This feature strongly supports the organic origin of the phenomenon. The pathophysiology of this phenomenon, however, remains unclear; the hypothesis of a lower threshold for perception of entoptic images cannot entirely account for the reported symptoms.

摘要

引言

视雪症是一些患者描述的一种症状,但眼科医生对此认识不足。它表现为持续感觉到视野中有纹理或呈雪花状,有时伴有视觉残留、对蓝视标内视现象的过度感知和畏光。我们报告一组患有视雪症的患者,以明确其特征并讨论其病理生理学。

材料与方法

对2010年9月至2012年12月间诊断为视雪现象的患者进行前瞻性研究。对每位患者进行了正式的眼科检查、阿姆斯勒方格表测试、自动视野检查(中心20°)、色觉测试(15色相)、全视野、图形和多焦视网膜电图以及闪光和图形视觉诱发电位(Métrovision)检查。未系统地进行脑部成像检查。

结果

纳入了12名年龄在9至48岁的患者(6名男性和6名女性,85%为学生)。几种体征与视雪现象有不同程度的关联:视觉残留(50%)、持续的蓝视标内视现象(40%)、畏光(30%)、偏头痛(30%);在20%的病例中,发现有初始毒物摄入情况(20%)。

讨论

本研究突出了报告视雪现象的患者所描述的典型症状的可重复性。这一特征有力地支持了该现象的器质性起源。然而,这一现象的病理生理学仍不清楚;内视图像感知阈值降低的假说不能完全解释所报告的症状。

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