van Assen Tijmen, Boelens Oliver B, van Eerten Percy V, Perquin Christel, Scheltinga Marc R, Roumen Rudi M
Department of Surgery, Máxima Medical Center, Eindhoven/Veldhoven, The Netherlands.
Department of Surgery, Maasziekenhuis Pantein, Boxmeer, The Netherlands.
Surgery. 2015 Jan;157(1):137-43. doi: 10.1016/j.surg.2014.05.022. Epub 2014 Oct 14.
Surgery occasionally is proposed in patients with chronic abdominal wall pain caused by an anterior cutaneous nerve entrapment syndrome (ACNES) who are refractory to injection therapy. An anterior neurectomy may seem successful, but follow-up is usually short and populations are small. The primary aim of this study was to determine the long-term success rate of surgery in a large ACNES population.
In this retrospective observational study, patients with ACNES ≥18 years who underwent a primary anterior neurectomy between January 2004 and February 2012 in one single center were studied. Pain scores were obtained before surgery, after surgery, and at the moment of questioning using a pain intensity numeric rating scale (PI-NRS 0-10) and a 6-point verbal category rating scale. Success was defined as a ≥50% PI-NRS reduction or ≥2 point verbal rating scale reduction.
Data of 181 neurectomies in 154 individuals were available for analysis (female, n = 127, 82.5%; age 47 ± 17 years, range, 20-83). Pain before operation was severe (mean PI-NRS 8.08, SD 1.43). Short-term (1-3 months postoperative) success was 70% (127/181 procedures). Three subjects showed spontaneous remission of complaints after ≥3 months. After a mean 32 months (range, 3-93) follow-up, a success rate of 61% (109/180) on the long-term was found.
A 70% short-term success rate and a 61% long-term success rate after a primary anterior neurectomy in patients with chronic abdominal pain due to ACNES were attained. Surgery is the method of choice in ACNES patients who are refractory to a conservative regimen.
对于因前皮神经卡压综合征(ACNES)导致慢性腹壁疼痛且注射治疗无效的患者,偶尔会建议进行手术。前路神经切除术看似成功,但随访时间通常较短且样本量较小。本研究的主要目的是确定在大量ACNES患者群体中手术的长期成功率。
在这项回顾性观察研究中,对2004年1月至2012年2月在单一中心接受初次前路神经切除术的年龄≥18岁的ACNES患者进行了研究。在手术前、手术后以及询问时使用疼痛强度数字评定量表(PI-NRS 0-10)和6点言语分类评定量表获取疼痛评分。成功定义为PI-NRS降低≥50%或言语评定量表降低≥两个等级。
154例患者的181例神经切除术数据可供分析(女性127例,占82.5%;年龄47±17岁,范围20-83岁)。术前疼痛严重(平均PI-NRS 8.08,标准差1.43)。短期(术后1-3个月)成功率为70%(127/181例手术)。3例患者在≥3个月后症状自发缓解。经过平均32个月(范围3-93个月)的随访,长期成功率为61%(109/180)。
对于因ACNES导致慢性腹痛的患者,初次前路神经切除术后短期成功率为70%,长期成功率为61%。手术是对保守治疗方案无效的ACNES患者的首选治疗方法。