Kheĭfets S N, Duda T L, Kurasov V N
Akush Ginekol (Mosk). 1989 May(5):31-3.
Blood kallikrein-kinin system (KKS) was studied in 80 pregnant women with gestoses of various severity and in 20 females with normal pregnancy. Kinin-formation and degradation were analysed and the exhaustion of these processes stated. Its degree was found in proportion with gestosis severity. Prekallikrein levels depended on the predominance of hypertensive disease or albuminuria occurrence. The aforementioned exhaustion possibly resulted from the preliminary activation of kallikrein-kinin system links which took place at the initial stages of gestosis to promote the adjustment of female circulation to increased loads.
对80例患有不同严重程度妊娠中毒症的孕妇和20例正常妊娠女性的血液激肽释放酶-激肽系统(KKS)进行了研究。分析了激肽的形成和降解情况,并指出了这些过程的耗竭。发现其程度与妊娠中毒症的严重程度成正比。前激肽释放酶水平取决于高血压疾病或蛋白尿的优势情况。上述耗竭可能是由于妊娠中毒症初始阶段激肽释放酶-激肽系统环节的初步激活所致,这有助于女性循环系统适应增加的负荷。