Li H, Wang Y, Oni J K, Qu X, Li T, Zeng Y, Liu F, Zhu Z
Shanghai No. 9th People's Hospital, Department of Orthopaedics, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China.
Department of Orthopaedics, Rush University Medical Center, Chicago, Illinois 60612, USA.
Bone Joint J. 2014 Dec;96-B(12):1586-93. doi: 10.1302/0301-620X.96B12.33983.
There have been several studies examining the association between the morphological characteristics seen in acetabular dysplasia and the incidence of the osteoarthritis (OA). However, most studies focus mainly on acetabular morphological analysis, and few studies have scrutinised the effect of femoral morphology. In this study we enrolled 36 patients with bilateral acetabular dysplasia and early or mid-stage OA in one hip and no OA in the contralateral hip. CT scans were performed from the iliac crest to 2 cm inferior to the tibial tuberosity, and the morphological characteristics of both acetabulum and femur were studied. In addition, 200 hips in 100 healthy volunteer Chinese adults formed a control group. The results showed that the dysplastic group with OA had a significantly larger femoral neck anteversion and a significantly shorter abductor lever arm than both the dysplastic group without OA and the controls. Femoral neck anteversion had a significant negative correlation with the length of the abductor lever arm and we conclude that it may contribute to the development of OA in dysplastic hips.
已有多项研究探讨髋臼发育不良的形态学特征与骨关节炎(OA)发病率之间的关联。然而,大多数研究主要集中在髋臼形态分析上,很少有研究仔细研究股骨形态的影响。在本研究中,我们纳入了36例双侧髋臼发育不良且一侧髋关节处于早期或中期OA而对侧髋关节无OA的患者。从髂嵴至胫骨结节下方2 cm进行CT扫描,并研究髋臼和股骨的形态学特征。此外,100名健康中国成年志愿者的200个髋关节组成了对照组。结果显示,患有OA的发育不良组的股骨颈前倾角明显更大,外展肌杠杆臂明显更短,与未患OA的发育不良组和对照组相比均是如此。股骨颈前倾角与外展肌杠杆臂长度呈显著负相关,我们得出结论,它可能促成发育不良髋关节OA的发生。