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社会经济地位和性别对 1 型和 2 型糖尿病患者血糖控制、心血管危险因素和糖尿病并发症的影响:苏格兰某地区的一项基于人群的分析。

Impact of socioeconomic status and gender on glycaemic control, cardiovascular risk factors and diabetes complications in type 1 and 2 diabetes: a population based analysis from a Scottish region.

机构信息

Department of General Medicine, The Ayr Hospital, NHS Ayrshire & Arran, KA6 6DX, United Kingdom.

AMRI Institute of Diabetes and Hormonal Disorders, 38/1A Gariahat Road, 700029 Kolkata, India.

出版信息

Diabetes Metab. 2015 Apr;41(2):145-51. doi: 10.1016/j.diabet.2014.09.004. Epub 2014 Nov 14.

Abstract

AIMS

In this cross-sectional study, the aims were to investigate the association of the socioeconomic status and gender on the prevalence of type 1 and 2 diabetes, glycaemic control, cardiovascular risk factors plus the complications of diabetes in a population-based analysis in the county of Ayrshire and Arran, Scotland.

METHODS

Quality Outcome Framework data was obtained from General Practices in Ayrshire and Arran, Scotland (n=15,351 patients).

RESULTS

In type 1 diabetes, there was an increasing linear trend in HbA1c across deprivation levels (P<0.01). In type 1 diabetes, obesity in women (P<0.01) and increased non-fasting triglyceride levels in both men and women were associated with deprivation (P<0.05). In type 2 diabetes, there was a significant prevalence trend with deprivation for women (P<0.01) but not with glycaemic control (P=0.12). Smoking, ischaemic heart disease and neuropathy (P<0.01) were all associated with increasing deprivation with gender differences. In type 2 diabetes, reduced HDL cholesterol (P<0.01 both genders), and percentage of people on lipid lowering therapy (men P<0.05; women P<0.01) were associated with deprivation. Smoking, ischaemic heart disease, peripheral vascular disease and neuropathy plus foot ulcers (P<0.05) were all associated with increasing deprivation with gender differences.

CONCLUSIONS

Socioeconomic status and gender are associated with changes in glycaemic control and cardiovascular risk factors plus complication development in both type 1 and 2 diabetes. The mechanisms are unclear but follow-up of these patients should allow greater understanding.

摘要

目的

在这项横断面研究中,我们旨在调查社会经济地位和性别对苏格兰艾尔郡和阿伦县基于人群的分析中 1 型和 2 型糖尿病、血糖控制、心血管危险因素以及糖尿病并发症患病率的影响。

方法

从苏格兰艾尔郡和阿伦的全科医生处获得了质量成果框架数据(n=15351 例患者)。

结果

在 1 型糖尿病中,HbA1c 随贫困程度呈线性增加趋势(P<0.01)。在 1 型糖尿病中,女性肥胖(P<0.01)和男女非空腹甘油三酯水平升高与贫困有关(P<0.05)。在 2 型糖尿病中,女性的患病率随贫困程度呈显著趋势(P<0.01),但血糖控制无此趋势(P=0.12)。吸烟、缺血性心脏病和神经病变(P<0.01)均与性别差异相关的贫困程度增加有关。在 2 型糖尿病中,降低的高密度脂蛋白胆固醇(男女均 P<0.01)和使用降脂药物的人群比例(男性 P<0.05;女性 P<0.01)与贫困程度有关。吸烟、缺血性心脏病、外周血管疾病和神经病变加足部溃疡(P<0.05)均与性别差异相关的贫困程度增加有关。

结论

社会经济地位和性别与 1 型和 2 型糖尿病的血糖控制和心血管危险因素及并发症的发展变化有关。其机制尚不清楚,但对这些患者的随访将有助于更好地理解。

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