正电子发射断层扫描（PET）及PET/计算机断层扫描的成本效益：一项系统评价

Cost-effectiveness of PET and PET/computed tomography: a systematic review.

作者信息

Gerke Oke, Hermansson Ronnie, Hess Søren, Schifter Søren, Vach Werner, Høilund-Carlsen Poul Flemming

机构信息

Department of Nuclear Medicine, Odense University Hospital, Søndre Boulevard 29, Odense 5000, Denmark; Department of Business and Economics, Centre of Health Economics Research, University of Southern Denmark, Campusvej 55, Odense M 5230, Denmark.

Institute of Clinical Research, University of Southern Denmark, Winsløwparken 19, 3 sal, Odense 5000, Denmark.

出版信息

PET Clin. 2015 Jan;10(1):105-24. doi: 10.1016/j.cpet.2014.09.008. Epub 2014 Oct 14.

DOI:10.1016/j.cpet.2014.09.008

PMID:25455883

Abstract

The development of clinical diagnostic procedures comprises early-phase and late-phase studies to elucidate diagnostic accuracy and patient outcome. Economic assessments of new diagnostic procedures compared with established work-ups indicate additional cost for 1 additional unit of effectiveness measure by means of incremental cost-effectiveness ratios when considering the replacement of the standard regimen by a new diagnostic procedure. This article discusses economic assessments of PET and PET/computed tomography reported until mid-July 2014. Forty-seven studies on cancer and noncancer indications were identified but, because of the widely varying scope of the analyses, a substantial amount of work remains to be done.

摘要

临床诊断程序的开发包括早期和晚期研究，以阐明诊断准确性和患者预后。与既定检查方法相比，新诊断程序的经济评估表明，在考虑用新诊断程序替代标准方案时，通过增量成本效益比，每增加1个单位的有效性指标会产生额外成本。本文讨论了截至2014年7月中旬报道的正电子发射断层扫描（PET）和PET/计算机断层扫描的经济评估。共确定了47项关于癌症和非癌症适应症的研究，但由于分析范围差异很大，仍有大量工作有待完成。