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计算机断层扫描用于识别重症外科患者潜在的感染源。

Computed tomography for the identification of a potential infectious source in critically ill surgical patients.

作者信息

Just Katja S, Defosse Jérôme M, Grensemann Joern, Wappler Frank, Sakka Samir G

机构信息

Department of Anesthesiology and Intensive Care Medicine, University of Witten/Herdecke, Cologne-Merheim Medical Center, Köln, Germany.

Department of Anesthesiology and Intensive Care Medicine, University of Witten/Herdecke, Cologne-Merheim Medical Center, Köln, Germany.

出版信息

J Crit Care. 2015 Apr;30(2):386-9. doi: 10.1016/j.jcrc.2014.10.013. Epub 2014 Oct 22.

Abstract

INTRODUCTION

Computed tomography (CT) seems already to have an important role to identify an infectious source in the management of patients with sepsis. However, our daily clinical behavior in ordering CT imaging was never scrutinized.

METHODS

We conducted a retrospective single-center analysis of CT and its therapeutic consequences in an operative intensive care unit in a tertiary care hospital in Germany. All CTs of the abdomen and/or thorax between 1st January and 31st December 2012 were included. One hundred forty-four CT studies were enrolled: 60.4% visceral, 6.9% vascular, 17.4% thoracic, and 14.6% trauma surgical cases and in 0.7% other disciplines.

RESULTS

In 76 CT studies (52.8%), a source of infection was found and was associated with a change in treatment in 65 (85.5%) cases. In contrast, in patients without identification of an infectious source in the CT imaging, treatment was changed after CT imaging in 11 (16.2%) cases. Computed tomography provided positive findings predominantly in the organ or the region of the surgical field.

CONCLUSIONS

Computed tomographic imaging detected an infectious source in more than 50% of cases. Our data suggest that CT should be recommended to identify a source of infection in critically ill patients. Furthermore, prospective studies are needed to investigate the potential impact of CT imaging on outcome and to define criteria when to perform a CT imaging study.

摘要

引言

在脓毒症患者的管理中,计算机断层扫描(CT)似乎已在识别感染源方面发挥重要作用。然而,我们日常开具CT影像检查的临床行为从未受到审视。

方法

我们对德国一家三级医院手术重症监护病房的CT及其治疗结果进行了回顾性单中心分析。纳入了2012年1月1日至12月31日期间所有腹部和/或胸部的CT检查。共纳入144项CT研究:60.4%为内脏疾病,6.9%为血管疾病,17.4%为胸部疾病,14.6%为创伤外科病例,0.7%为其他学科病例。

结果

在76项CT研究(52.8%)中发现了感染源,其中65例(85.5%)的治疗方案发生了改变。相比之下,在CT影像中未发现感染源的患者中,有11例(16.2%)在CT检查后治疗方案发生了改变。计算机断层扫描主要在手术区域的器官或部位发现了阳性结果。

结论

计算机断层扫描成像在超过50%的病例中检测到了感染源。我们的数据表明,对于重症患者,应推荐使用CT来识别感染源。此外,需要进行前瞻性研究,以调查CT成像对治疗结果的潜在影响,并确定何时进行CT成像检查的标准。

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