Li Fan, Zaslavsky Alan M
Department of Statistical Science, Duke University.
Department of Health Care Policy, Harvard Medical School.
J Am Stat Assoc. 2010 Dec;105(492):1323-1332. doi: 10.1198/jasa.2010.ap09185.
We use data collected in the National Comorbidity Survey - Adolescent (NCS-A) to develop a methodology to estimate the small-area prevalence of serious emotional distress (SED) in schools in the United States, exploiting the clustering of the main NCS-A sample by school. The NCS-A instrument includes both a short screening scale, the K6, and extensive diagnostic assessments of the individual disorders and associated impairment that determine the diagnosis of SED. We fitted a Bayesian bivariate multilevel regression model with correlated effects for the probability of SED and a modified K6 score at the individual and school levels. Our results provide evidence for the existence of variation in the prevalence of SED across schools and geographical regions. Although the concordance between the modified K6 scale and SED is only modest for individuals, the school-level random effects for the two measures are strongly correlated. Under this model we obtain a prediction equation for the rate of SED based on the mean K6 score and covariates. This finding supports the feasibility of using short screening scales like the K6 as an alternative to more comprehensive lay assessments in estimating school-level rates of SED. These methods may be applicable to other studies aiming at small-area estimation for geographical units.
我们使用全国共病调查青少年版(NCS-A)收集的数据,开发一种方法来估计美国学校中严重情绪困扰(SED)的小区域患病率,利用NCS-A主要样本按学校聚类的特点。NCS-A工具既包括一个简短的筛查量表K6,也包括对个体障碍及相关损害的广泛诊断评估,这些评估决定了SED的诊断。我们拟合了一个贝叶斯双变量多层次回归模型,该模型在个体和学校层面上对SED概率和修正后的K6分数具有相关效应。我们的结果为SED患病率在不同学校和地理区域存在差异提供了证据。尽管修正后的K6量表与SED之间对于个体的一致性仅为中等程度,但这两种测量在学校层面的随机效应高度相关。在这个模型下,我们基于平均K6分数和协变量得到了SED发生率的预测方程。这一发现支持了使用像K6这样的简短筛查量表作为在估计学校层面SED发生率时替代更全面的外行评估的可行性。这些方法可能适用于其他旨在对地理单位进行小区域估计的研究。