Haghjoo Majid, Salem Nasim, Rafati Masoud, Fazelifar Amirfarjam
Cardiac Electrophysiology Research Center, Rajaie Cardiovascular Medical and Research Center, Tehran University of Medical Sciences, Tehran, IR Iran.
Rajaie Cardiovascular Medical and Research Center, Tehran University of Medical Sciences, Tehran, IR Iran.
Res Cardiovasc Med. 2013 May;2(2):90-4. doi: 10.5812/cardiovascmed.9061. Epub 2013 May 20.
Despite technical refinements and improved long-term efficacy of the ablation procedure for treating AFL (AFL), the subsequent occurrence of AF (AF) following this procedure remains a significant clinical problem.
To determine long-term incidence and predictors of AF after catheter ablation of typical AFL.
Between March 2005 and February 2010, a total of 84 consecutive patients who underwent catheter ablation of documented typical AFL were enrolled.
Cavotricuspid isthmus ablation was successful in terminating and preventing the re-induction of AFL in all 84 patients (100%). The mean follow-up duration for study was 26± 22 months. During the follow-up period, early AF occurred in 5% after successful catheter ablation of AFL and late AF in 11% of the patients. The clinical variables associated with the occurrence of AF after catheter ablation of AFL were female, a history of AF before AFL ablation, body mass index (BMI), and left atrial abnormality. However, logistic multivariate analysis demonstrated that only BMI was independently associated with the late AF (OR 1.36, 95% CI 1.11-1.70, P = 0.004).
Catheter ablation of flutter circuit will not prevent later manifestation of AF in 16% of the patients undergoing catheter ablation of the typical AFL. BMI was the only independent predictor of AF following catheter ablation of the typical AFL.
尽管在治疗典型心房扑动(AFL)的消融手术方面技术有所改进且长期疗效有所提高,但该手术后随后发生心房颤动(AF)仍然是一个重大的临床问题。
确定典型AFL导管消融术后AF的长期发生率及预测因素。
2005年3月至2010年2月,共纳入84例连续接受记录在案的典型AFL导管消融术的患者。
在所有84例患者(100%)中,三尖瓣峡部消融成功终止并预防了AFL的再次诱发。研究的平均随访时间为26±22个月。在随访期间,AFL导管消融成功后5%的患者发生早期AF,11%的患者发生晚期AF。与AFL导管消融术后AF发生相关的临床变量为女性、AFL消融术前有AF病史、体重指数(BMI)和左心房异常。然而,多因素逻辑回归分析表明,只有BMI与晚期AF独立相关(OR 1.36,95%CI 1.11 - 1.70,P = 0.004)。
在接受典型AFL导管消融术的患者中,16%的患者进行flutter环导管消融并不能预防AF的后期表现。BMI是典型AFL导管消融术后AF的唯一独立预测因素。