Mozaffari Kambiz, Bakhshandeh Hooman, Khalaj Hadi, Soudi Hengameh
Rajaie Cardiovascular, Medical and Research Center, Tehran University of Medical Sciences, Tehran, IR Iran.
Cardiovascular Intervention Research Center, Rajaie Cardiovascular, Medical and Research Center, Tehran University of Medical Sciences, Tehran, IR Iran.
Res Cardiovasc Med. 2013 May;2(2):99-103. doi: 10.5812/cardiovascmed.9388. Epub 2013 May 20.
Catheter Related Blood stream Infections (CRBSI) are prevalent and a potentially fatal complication pertaining to cardiovascular implant devices. There have been no major studies on bacterial colonization of catheters in cardiovascular patients in Iran.
To evaluate the incidence of catheter colonization of bacteria in the largest Iranian cardiovascular center.
March 2011 to 2012, Cauterization procedures performed on 60 patients hospitalized in Rajaie Cardiovascular Medical and Research Center, Tehran, Iran, with arterial or venous catheterization, inserted 48 hours or more, catheter evaluations done by culture methods. Blood cultures were also obtained simultaneously.
Forty-four out of 60 catheters (73.3%) were positive with a significant colony count. Of 44 positive cases, 11 patients had positive blood culture. Three most frequently isolated microorganisms were Staph Albus [14 (32%)], Entrococcu [12 (27%)] and Acinetobacter [5 (11%)]. gram-positive cocci were sensitive to Vancomycin and Linezolid and gram-negative bacilli were sensitive to Amikacin, Gentamicin, Tobramycin and Imipenem.
The study findings revealed that the catheter infection in our patients had sources other than normal skin flora. These results will assist in determining the possible source of the infections, furthermore, how they are transmitted, moreover aid in controlling and preventing these dangerous in- infections.
导管相关血流感染(CRBSI)很常见,是心血管植入装置潜在的致命并发症。伊朗尚未有关于心血管疾病患者导管细菌定植的重大研究。
评估伊朗最大的心血管中心导管细菌定植的发生率。
2011年3月至2012年,对伊朗德黑兰拉贾伊心血管医学与研究中心住院的60例患者进行了烧灼手术,这些患者进行了动脉或静脉插管,插管时间在48小时或更长时间,通过培养方法对导管进行评估。同时也采集了血培养样本。
60根导管中有44根(73.3%)菌落计数显著,培养呈阳性。在44例阳性病例中,11例患者血培养呈阳性。三种最常分离出的微生物是白色葡萄球菌[14例(32%)]、肠球菌[12例(27%)]和不动杆菌[5例(11%)]。革兰氏阳性球菌对万古霉素和利奈唑胺敏感,革兰氏阴性杆菌对阿米卡星、庆大霉素、妥布霉素和亚胺培南敏感。
研究结果表明,我们患者的导管感染来源并非正常皮肤菌群。这些结果将有助于确定感染的可能来源,以及感染的传播方式,进而有助于控制和预防这些危险的感染。