Mozaffari Kambiz, Bakhshandeh Hooman, Soudi Hengameh
Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, IR Iran.
Res Cardiovasc Med. 2014 Aug;3(3):e19432. doi: 10.5812/cardiovascmed.19432. Epub 2014 Aug 15.
Bacterial pericarditis is an important cause of post-surgery mortality and morbidity. This can be a preventable complication and the involved pathogens vary according to the time and location.
The aim of this study was to investigate the bacteriologic profile in patients with pericardial infections after cardiac surgery in the largest tertiary care center for cardiovascular diseases in Iran. The results can be applied for prevention, diagnosis, and treatment of similar patients in Iran.
This prospective study was performed in Rajaie Cardiovascular Medical and Research Center (RCMRC), the largest tertiary care center for cardiovascular disease in Iran from March 2011 to March 2012. Patients who had undergone cardiac surgery with cardiopulmonary bypass and showed suggestive sign and symptoms of pericardial infections were registered and samples from their pericardial fluids were obtained to perform standard bacteriologic and antibiogram tests.
A total of 158 patients were registered. Bacteriologic findings were positive in 30 patients (19%). Staphylococcus epidermidis was the most frequent isolated organism, which was found in 22 patients (73.3%) with eight of them being methicillin-resistant strains.
The bacteriologic profile in our patient is specific to our own community. Knowledge about this profile can help us to improve prevention, diagnosis, and treatment of the affected patients.
细菌性心包炎是术后死亡和发病的重要原因。这是一种可预防的并发症，所涉及的病原体因时间和地点而异。
本研究旨在调查伊朗最大的心血管疾病三级护理中心心脏手术后心包感染患者的细菌学特征。研究结果可应用于伊朗类似患者的预防、诊断和治疗。
这项前瞻性研究于2011年3月至2012年3月在伊朗最大的心血管疾病三级护理中心拉贾伊心血管医学与研究中心（RCMRC）进行。对接受体外循环心脏手术并出现心包感染相关体征和症状的患者进行登记，并采集心包液样本进行标准细菌学和药敏试验。
共登记了158例患者。30例患者（19%）细菌学检查结果呈阳性。表皮葡萄球菌是最常分离出的病原体，在22例患者（73.3%）中发现，其中8例为耐甲氧西林菌株。
我们患者的细菌学特征是我们所在社区特有的。了解这一特征有助于我们改善对受影响患者的预防、诊断和治疗。
