Chen Mang L, Odom Brian D, Santucci Richard A
Department of Urology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Can J Urol. 2014 Dec;21(6):7565-9.
To evaluate the efficacy of transecting anastomotic urethroplasty (AU) and buccal mucosa graft (BMG) ventral onlay substitution urethroplasty (SU) in treating short bulbar urethral strictures.
Sixty patients underwent either AU or SU for bulbar strictures of similar length with follow up of at least 12 months. Follow up included clinical history, uroflowmetry, and ultrasound post-void residuals (PVR) performed every 4 months for the first year and yearly thereafter.
Out of 131 patients with short bulbar strictures, 40 were treated with BMG onlay SU and 20 had AU. Median follow up in the SU group was 57 months (IQR 27-76) and 120 months (IQR 109-130) in the AU group. The median stricture length was 3 cm (IQR 2.5-3.0) in the SU group and 1.3 cm (IQR 1-2) in the AU group (p < 0.001). The 3 year freedom from intervention was 93% in the SU group, and 85% in the AU group (p = 0.72).
BMG onlay ventral urethroplasty has similar success rates to anastomotic urethroplasty for short bulbar urethral strictures. Due to the relatively fewer complications reported after substitution urethroplasty with BMG, it should be considered the treatment of choice for short bulbar urethral strictures.
评估横断吻合性尿道成形术(AU)和颊黏膜移植(BMG)腹侧镶嵌替代尿道成形术(SU)治疗短段球部尿道狭窄的疗效。
60例患者因长度相似的球部狭窄接受了AU或SU治疗,随访至少12个月。随访内容包括临床病史、尿流率测定以及术后残余尿量(PVR)超声检查,术后第一年每4个月进行一次,此后每年进行一次。
在131例短段球部尿道狭窄患者中,40例接受了BMG镶嵌SU治疗,20例接受了AU治疗。SU组的中位随访时间为57个月(四分位间距27 - 76),AU组为120个月(四分位间距109 - 130)。SU组狭窄的中位长度为3 cm(四分位间距2.5 - 3.0),AU组为1.3 cm(四分位间距1 - 2)(p < 0.001)。SU组3年无干预生存率为93%,AU组为85%(p = 0.72)。
对于短段球部尿道狭窄,BMG腹侧尿道成形术与吻合性尿道成形术的成功率相似。由于BMG替代尿道成形术后报告的并发症相对较少,它应被视为短段球部尿道狭窄的首选治疗方法。