胶原-羟基磷灰石/果胶复合材料的制备与表征。
Preparation and characterization of collagen-hydroxyapatite/pectin composite.
机构信息
School of Medical Technology and Engineering, Henan University of Science and Technology, Luoyang 471003, Henan, China; School of Materials Science and Engineering, Zhengzhou University, Zhengzhou 450001, Henan, China.
School of Medical Technology and Engineering, Henan University of Science and Technology, Luoyang 471003, Henan, China.
出版信息
Int J Biol Macromol. 2015 Mar;74:218-23. doi: 10.1016/j.ijbiomac.2014.11.031. Epub 2014 Dec 6.
Pectin, a kind of plant polysaccharide, was introduced into collagen-hydroxyapatite composite system, and prepared collagen-hydroxyapatite/pectin (Col-HA/pectin) composite in situ. The structure of the composite was investigated by XRD, SEM, and FT-IR. The mechanical properties, water absorption, enzyme degradation, and cytotoxicity of the composite were investigated as well. The results show that the inorganic substance in the composite materials is hydroxyapatite in relatively low crystallinity. A new interface appeared by the interaction among hydroxyapatite and collagen-pectin, and formed smooth fine particles. The mechanical properties, water absorption, enzyme degradation, and cytotoxicity indicate a potential use in bone replacement for the new composite.
果胶是一种植物多糖，被引入到胶原-羟基磷灰石复合体系中，原位制备了胶原-羟基磷灰石/果胶（Col-HA/pectin）复合材料。采用 XRD、SEM 和 FT-IR 对复合材料的结构进行了研究。同时还研究了复合材料的力学性能、吸水率、酶降解和细胞毒性。结果表明，复合材料中的无机物质为相对低结晶度的羟基磷灰石。通过羟基磷灰石与胶原-果胶的相互作用，出现了新的界面，形成了光滑的细小颗粒。新复合材料的力学性能、吸水率、酶降解和细胞毒性表明其在骨替代方面具有潜在的应用价值。
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