Yang Edmund Y, Davies Lauren M, Buchanan Paula, Kling Catherine, Banyard Derek A, Ramones Theresa
Department of Pediatric Surgery, Children's Hospital of Illinois, Peoria, Illinois, 61603.
Saint Louis University School of Medicine, Saint Louis, Missouri, 63104.
J Pediatr Surg. 2014 Dec;49(12):1776-81. doi: 10.1016/j.jpedsurg.2014.09.021. Epub 2014 Oct 12.
BACKGROUND/PURPOSE: We studied obstetric delivery practices for fetal gastroschisis and correlated this with neonatal outcomes. Our objectives were to identify changes in delivery practices over time and to determine if these changes resulted in improved neonatal outcomes.
After IRB approval, maternal and neonatal records from 219 gastroschisis births between 1990 and 2008 were reviewed. Obstetrical data and neonatal data were collected. Univariate comparisons were made between maternal delivery variables and neonatal outcomes. Significant and clinically relevant obstetrical variables were combined for multivariate linear regression modeling.
The practice of elective cesarean delivery (ELCS) shifted to spontaneous vaginal delivery (sVD) over time (p <0.001). Babies born by sVD had longer hospitalization than those born by ELCS (median 36.0 vs 21.6days, p <0.05). Gestational age (GA) and birth weight were similar between groups. Babies born by induced VD (iVD) had short hospitalization (median 22.5days). A linear regression model demonstrated that spontaneous onset of labor (SOL) and GA were independently related to LOS.
Over nearly two decades, delivery of gastroschisis babies shifted from ELCS to sVD, a practice associated with a significantly longer LOS. Regression models suggest that shorter LOS could be achieved if elective delivery modes are utilized prior to SOL.
背景/目的:我们研究了胎儿腹裂的产科分娩方式,并将其与新生儿结局相关联。我们的目标是确定分娩方式随时间的变化,并确定这些变化是否导致新生儿结局改善。
在获得机构审查委员会(IRB)批准后,回顾了1990年至2008年间219例腹裂分娩的孕产妇和新生儿记录。收集产科数据和新生儿数据。对孕产妇分娩变量和新生儿结局进行单因素比较。将具有显著意义和临床相关性的产科变量合并用于多变量线性回归建模。
随着时间的推移,选择性剖宫产(ELCS)的方式转变为自然阴道分娩(sVD)(p<0.001)。经sVD出生的婴儿住院时间比经ELCS出生的婴儿长(中位数分别为36.0天和21.6天,p<0.05)。两组之间的孕周(GA)和出生体重相似。经引产阴道分娩(iVD)出生的婴儿住院时间短(中位数22.5天)。线性回归模型表明,自然发动分娩(SOL)和GA与住院时间独立相关。
在近二十年中,腹裂婴儿的分娩方式从ELCS转变为sVD,这种方式与显著更长的住院时间相关。回归模型表明,如果在SOL之前采用选择性分娩方式,可能会缩短住院时间。