Amasyali Basri, Kilic Ayhan, Kabul Kutsi, Unlu Murat
Department of Cardiology, School of Medicine, Dumlupinar University, Kutahya, Turkey.
Department of Cardiology, Gulhane Military Medical School, Ankara, Turkey.
Postepy Kardiol Interwencyjnej. 2014;10(4):301-7. doi: 10.5114/pwki.2014.46775. Epub 2014 Nov 17.
Radiofrequency (RF) ablation of the slow pathway for treatment of atrioventricular nodal reentrant tachycardia (AVNRT) is conventionally performed during sinus rhythm.
To evaluate the clinical and electrophysiological features and the short- and long-term results of slow pathway RF ablation during ongoing AVNRT.
A total of 282 consecutive patients with AVNRT undergoing RF catheter ablation were analysed. Patients whose tachycardia episodes could not be controlled during RF energy application and who underwent slow pathway ablation or modification during ongoing tachycardia formed the study group (group 1, n = 16) and those ablated during sinus rhythm formed the control group (group 2, n = 266).
Of the clinical characteristics, only the frequency of tachycardia attacks was higher in group 1 (3.3 ±1.2 vs. 2.1 ±0.9 attacks/month, p < 0.001). Among the baseline electrophysiological measurements, the echo zone lasted significantly longer in group 1 than in group 2 (78 ±25 ms vs. 47 ±18 ms; p < 0.001). The immediate procedural success rate was 100% in both groups. There were no significant differences between groups regarding the mean number of radiofrequency energy applications (5.2 ±4.2 vs. 5.8 ±3.9), total procedure times (42.4 ±30.5 min vs. 40.2 ±29.4 min) and fluoroscopy times (11.4 ±8.5 min vs. 12.2 ±9.3 min) (p > 0.050 for all). All patients were followed-up for 29 ±7 months; only 2 patients (< 1%) in group 2 recurred (p > 0.050). No permanent atrioventricular block was observed.
The RF catheter ablation or modification of the slow pathway during ongoing AVNRT is feasible with acceptable short- and long-term efficacy and safety. However, this approach needs to be clarified with large-scale studies.
传统上,射频(RF)消融慢径路用于治疗房室结折返性心动过速(AVNRT)是在窦性心律下进行的。
评估在持续性AVNRT期间进行慢径路RF消融的临床和电生理特征以及短期和长期结果。
对连续282例接受RF导管消融治疗的AVNRT患者进行分析。在RF能量施加期间心动过速发作无法控制且在持续性心动过速期间接受慢径路消融或改良的患者形成研究组(第1组,n = 16),而在窦性心律下进行消融的患者形成对照组(第2组,n = 266)。
在临床特征方面,仅第1组的心动过速发作频率较高(3.3±1.2次/月对2.1±0.9次/月,p < 0.001)。在基线电生理测量中,第1组的回波区持续时间明显长于第2组(78±25毫秒对47±18毫秒;p < 0.001)。两组的即刻手术成功率均为100%。两组在平均射频能量施加次数(5.2±4.2次对5.8±3.9次)、总手术时间(42.4±30.5分钟对40.2±29.4分钟)和透视时间(11.4±8.5分钟对12.2±9.3分钟)方面无显著差异(所有p > 0.050)。所有患者均随访29±7个月;第2组仅2例患者(<1%)复发(p > 0.050)。未观察到永久性房室传导阻滞。
在持续性AVNRT期间进行RF导管消融或改良慢径路是可行的,短期和长期疗效及安全性均可接受。然而,这种方法需要通过大规模研究进一步明确。