Signorelli F, Della Pepa G M, Sabatino G, Marchese E, Maira G, Puca A, Albanese A
Institute of Neurosurgery, Catholic University of Rome, Rome, Italy.
Institute of Neurosurgery, Catholic University of Rome, Rome, Italy.
Clin Neurol Neurosurg. 2015 Jan;128:123-9. doi: 10.1016/j.clineuro.2014.11.011. Epub 2014 Nov 24.
Dural arteriovenous fistulas (DAVFs) are a challenging condition in vascular neurosurgery. Disease natural history and its management is still debated. In the present paper we report our center series on DAVFs over a period of 10 years. Our data were compared with relevant literature.
Our series includes 45 cases: 14 cavernous sinus, 11 transverse-sigmoid, 8 patients tentorial, 6 anterior cranial fossa, 5 patients spinal, 1 patient foramen magnum.
DVAFs distribution, clinical presentation and hemorrhagic risk are discussed. Cavernous sinus DAVFs are the most common site in our series. Other locations in order of frequency are transverse-sigmoid sinus, tentorial, anterior cranial fossa, spinal and foramen magnum. The majority of patients presented with non-aggressive symptoms. 18% presented with intracranial hemorrhage: all the hemorrhages occurred in high-grade DAVFs. For most patients, endovascular treatment, transarterial or transvenous, was the first option. Surgery was performed for the anterior cranial fossa DAVFs and other complex lesions draining mostly transverse-sigmoid sinus and tentorium. In 7% of cases a combination of endovascular+surgical treatment was used. Our series has been carefully analyzed in comparison 'side by side' with most relevant literature on DVAFs, focusing particularly on management strategies, therapeutic options and risks related to treatment.
硬脑膜动静脉瘘(DAVFs)是血管神经外科中具有挑战性的病症。疾病的自然史及其治疗方法仍存在争议。在本文中,我们报告了我们中心10年来关于DAVFs的病例系列。我们的数据与相关文献进行了比较。
我们的系列包括45例病例:海绵窦14例,横窦-乙状窦11例,小脑幕8例,前颅窝6例,脊柱5例,枕骨大孔1例。
讨论了DAVFs的分布、临床表现和出血风险。海绵窦DAVFs是我们系列中最常见的部位。其他部位按频率依次为横窦-乙状窦、小脑幕、前颅窝、脊柱和枕骨大孔。大多数患者表现为非侵袭性症状。18%的患者出现颅内出血:所有出血均发生在高级别DAVFs中。对于大多数患者,血管内治疗,经动脉或经静脉,是首选方案。前颅窝DAVFs和其他主要引流横窦-乙状窦和小脑幕的复杂病变采用手术治疗。7%的病例采用血管内+手术联合治疗。我们的系列与关于DAVFs的最相关文献进行了“并排”仔细分析,特别关注管理策略、治疗选择和与治疗相关的风险。