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302例连续接受全机器人胃旁路手术患者术后发病的危险因素

Risk Factors for Postoperative Morbidity After Totally Robotic Gastric Bypass in 302 Consecutive Patients.

作者信息

Fantola G, Nguyen-Thi P L, Reibel N, Sirveaux M A, Germain A, Ayav A, Bresler L, Zarnegar R, Brunaud L

机构信息

Department of Digestive, Hepato-Biliary and Endocrine Surgery, CHU Nancy-Hospital Brabois Adultes, University de Lorraine, 11 allée du morvan, 54511, Vandoeuvre-les-Nancy, France.

出版信息

Obes Surg. 2015 Jul;25(7):1229-38. doi: 10.1007/s11695-014-1530-5.

Abstract

BACKGROUND

Totally robotic gastric bypass (robotic Roux-en-Y gastric bypass, R-RYGBP) has been adopted in some centers on the basis of large retrospective studies. In view of some data showing higher morbidity and higher costs, some authors have considered that robotic gastric bypass may no longer be justified with the existing system. Although low postoperative complication rates after R-RYGBP have been reported, risk factors for postoperative morbidity have never been evaluated. The goal of this study was to identify risk factors for postoperative morbidity after R-RYGBP.

METHODS

A retrospective analysis of a prospectively maintained database was performed and included 302 consecutive patients after R-RYGBP performed between 2007 and 2013. This subset of patients represented 34 % of all gastric bypass procedures performed during this study period. Univariate and multivariate analyses were performed in order to identify risk factors for postoperative overall morbidity (Clavien scores 1-4 versus 0) and major morbidity (Clavien score ≥3 versus 0-1-2).

RESULTS

Postoperative morbidity and mortality rates were 24.4 and 0.6 %, respectively. In multivariate analysis, independent risk factors for overall morbidity were American Society of Anesthesiologists (ASA) score ≥3 (odds ratio (OR) 2.0) and previous bariatric surgery (revisional gastric bypass) (OR 2.0). Independent risk factors for major morbidity (Clavien ≥3) were previous bariatric surgery (revisional gastric bypass) (OR 3.7), low preoperative hematocrit level (OR 0.9), and revisional gastric bypass procedure with concomitant gastric banding removal (OR 5.7).

CONCLUSIONS

R-RYGBP is prone to increased complications in the setting of a high preoperative ASA score and revisional surgery. This should be taken into consideration by clinicians when evaluating R-RYGBP.

摘要

背景

在一些大型回顾性研究的基础上,全机器人胃旁路手术(机器人Roux-en-Y胃旁路手术,R-RYGBP)已在部分中心开展。鉴于一些数据显示其发病率较高且成本更高,一些作者认为在现有体系下机器人胃旁路手术可能不再合理。尽管已有报道称R-RYGBP术后并发症发生率较低,但术后发病的危险因素从未得到评估。本研究的目的是确定R-RYGBP术后发病的危险因素。

方法

对前瞻性维护的数据库进行回顾性分析,纳入2007年至2013年间连续接受R-RYGBP手术的302例患者。该患者亚组占本研究期间所有胃旁路手术的34%。进行单因素和多因素分析以确定术后总体发病率(Clavien评分1 - 4级与0级)和严重发病率(Clavien评分≥3级与0 - 1 - 2级)的危险因素。

结果

术后发病率和死亡率分别为24.4%和0.6%。在多因素分析中,总体发病率的独立危险因素是美国麻醉医师协会(ASA)评分≥3(比值比(OR)2.0)和既往减肥手术(翻修性胃旁路手术)(OR 2.0)。严重发病率(Clavien≥3级)的独立危险因素是既往减肥手术(翻修性胃旁路手术)(OR 3.7)、术前血细胞比容水平低(OR 0.9)以及翻修性胃旁路手术同时拆除胃束带(OR 5.7)。

结论

在术前ASA评分高和翻修手术的情况下,R-RYGBP容易出现更多并发症。临床医生在评估R-RYGBP时应考虑到这一点。

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